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首页> 外文期刊>World Journal of Gastroenterology >Using computed tomography scans to develop an ex-vivo gastric model
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Using computed tomography scans to develop an ex-vivo gastric model

机译：使用计算机断层扫描来建立离体胃模型

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The objective of this research was to use abdominal computed tomography (CT) scans to non-invasively quantify anthropometrical data of the human stomach and to concomitantly create an anatomically correct and distensible ex-vivo gastric model. Thirty-three abdominal CT scans of human subjects were obtained and were imported into reconstruction software to generate 3D models of the stomachs. Anthropometrical data such as gastric wall thickness, gastric surface area and gastric volume were subsequently quantified. A representative 3D computer model was exported into a selective laser sintering (SLS) rapid prototyping machine to create an anatomically correct solid gastric model. Subsequently, a replica wax template of the SLS model was created. A negative mould was offset around the wax template such that the offset distance was equivalent to that of the gastric wall thickness. A silicone with similar mechanical properties to the human stomach was poured into the offset. The lost wax manufacturing technique was employed to create a hollow distensible stomach model. 3D computer gastric models were generated from the CT scans. A hollow distensible silicone ex-vivo gastric model with similar compliance to that of the human stomach was created. The anthropometrical data indicated that there is no significant relationship between BMI and gastric surface area or gastric volume. There were inter-and intra-group differences between groups with respect to gastric wall thickness. This study demonstrates that abdominal CT scans can be used to both non-invasively determine gastric anthropometrical data as well as create realistic ex-vivo stomach models.
机译：这项研究的目的是使用腹部计算机断层扫描（CT）扫描来无创地量化人胃的人体测量数据，并随之创建解剖学上正确且可扩张的离体胃模型。获得了33位人类受试者的腹部CT扫描，并将其导入重建软件中以生成胃部3D模型。随后定量人体测量数据，例如胃壁厚度，胃表面积和胃体积。代表性的3D计算机模型已导出到选择性激光烧结（SLS）快速原型制作机中，以创建解剖学上正确的实体胃模型。随后，创建了SLS模型的复制蜡模板。负模围绕蜡模板偏移，使得偏移距离等于胃壁厚度的偏移距离。将具有与人胃相似的机械性能的有机硅倒入胶印中。采用失蜡制造技术来创建空心可扩张胃模型。从CT扫描生成3D计算机胃模型。创建了具有与人胃相似的顺应性的中空可扩张有机硅离体胃模型。人体测量数据表明，BMI与胃表面积或胃容量之间无显着关系。各组之间在胃壁厚度方面存在组间和组内差异。这项研究表明，腹部CT扫描可用于无创地确定胃人体测量数据以及创建逼真的离体胃模型。

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