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首页> 外文期刊>World Journal of Gastroenterology >Clinical significance of main pancreatic duct dilation on computed tomography: Single and double duct dilation
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Clinical significance of main pancreatic duct dilation on computed tomography: Single and double duct dilation

机译：主胰管扩张在计算机断层扫描上的临床意义：单管和双管扩张

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AIM: To study the patients with main pancreatic duct dilation on computed tomography (CT) and thereby to provide the predictive criteria to identify patients at high risk of significant diseases, such as pancreatic cancer, and to avoid unnecessary work up for patients at low risk of such diseases. METHODS: Patients with dilation of the main pancreatic duct on CT at Emory University Hospital in 2002 were identified by computer search. Clinical course and ultimate diagnosis were obtained in all the identified patients by abstraction of their computer database records. RESULTS: Seventy-seven patients were identified in this study. Chronic pancreatitis and pancreatic cancer were the most common causes of the main pancreatic duct dilation on CT. Although the majority of patients with isolated dilation of the main pancreatic duct (single duct dilation) had chronic pancreatitis, one-third of patients with single duct dilation but without chronic pancreatitis had pancreatic malignancies, whereas most of patients with concomitant biliary duct dilation (double duct dilation) had pancreatic cancer. CONCLUSION: Patients with pancreatic double duct dilation need extensive work up and careful follow-up since a majority of these patients are ultimately diagnosed with pancreatic cancer. Patients with single duct dilation, especially such patients without any evidence of chronic pancreatitis, also need careful follow-up since the possibility of pancreatic malignancy, including adenocarcinoma and intraductal papillary mucinous tumors, is still high.
机译：目的：通过计算机断层扫描（CT）研究主要胰管扩张的患者，从而提供预测标准，以识别具有重大疾病（例如胰腺癌）高风险的患者，并避免对低危患者进行不必要的检查这类疾病。方法：通过计算机搜索确定2002年埃默里大学医院CT扫描显示的主胰管扩张患者。通过对所有已识别患者的计算机数据库记录进行抽象，可以获得临床病程和最终诊断。结果：本研究确定了77例患者。慢性胰腺炎和胰腺癌是CT上主要胰管扩张的最常见原因。尽管大多数主胰管孤立扩张（单管扩张）的患者患有慢性胰腺炎，但单管扩张但无慢性胰腺炎的患者中有三分之一患有胰腺恶性肿瘤，而大多数伴有胆管扩张的患者（双管扩张）导管扩张）患有胰腺癌。结论：胰腺双管扩张患者需要大量的检查和仔细的随访，因为这些患者中的大多数最终被诊断出患有胰腺癌。单管扩张的患者，尤其是没有任何慢性胰腺炎迹象的患者，也需要仔细随访，因为胰腺恶性肿瘤（包括腺癌和导管内乳头状粘液性肿瘤）的可能性仍然很高。

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