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首页> 外文期刊>World Journal of Gastroenterology >Helicobacter pylori infection in the pharynx of patients with chronic pharyngitis detected with TDI-FP and modified Giemsa stain.
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Helicobacter pylori infection in the pharynx of patients with chronic pharyngitis detected with TDI-FP and modified Giemsa stain.

机译：用TDI-FP和改良的Giemsa染色检测到的慢性咽炎患者咽部的幽门螺杆菌感染。

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AIM: To detect whether there is Helicobacter pylori (H pylori) colonization in the pharynx mucous membrane of healthy people and whether chronic pharyngitis is related to H pylori infection. METHODS: Fifty cases of chronic pharyngitis refractory over three months were prospectively studied from March 2004 to August 2004 in the otolaryngology outpatient department of the Second Hospital of Xi'an Jiaotong University. Template-directed dye-terminator incorporated with fluorescence polarization detection (TDI-FP) and modified Giemsa stain were used to examine pharynx mucous membrane tissue for H pylori colonization in the patients with chronic pharyngitis and the healthy people as a control group. RESULTS: In the control group, no people were detected to have H pylori in the pharynx. In contrast, in 50 cases with chronic pharyngitis, 19 (38.0%) cases were H pylori positive with a TDI-FP assay and 4 (8%) cases were TDI-FP positive with Giemsa staining in the pharynx. Sixteen of the 50 pharyngitis cases had stomach ailment history, 11 cases (68.8%) of these 16 patients were determined to be H pylori positive in the pharynx with the TDI-FP assay. c2 test showed that this infection rate was remarkably higher (P=0.0007) than that in the cases without stomach ailment history. Giemsa staining showed that 3 cases (18.8%) of the patients with stomach ailment history were infected with H pylori in the pharynx, which was remarkably higher (P=0.042) than that in the patients without stomach ailment history (1 case, which was 2.9%). CONCLUSION: H pylori may not be detected in the pharynx of healthy people. Chronic pharyngitis may be related to H pylori infection. The infection rate with H pylori in the pharynx is higher in patients with stomach ailment histories than in patients without stomach ailment histories, suggesting that chronic pharyngitis may be related to stomach ailment history.
机译：目的：检测健康人的咽粘膜中是否存在幽门螺杆菌（H pylori）的定植，以及慢性咽炎是否与幽门螺杆菌感染有关。方法：对2004年3月至2004年8月在西安交通大学第二医院耳鼻喉科门诊的50例3个月以上的慢性咽炎难治性病例进行前瞻性研究。模板导向的染料终止剂结合了荧光偏振检测（TDI-FP）和改良的Giemsa染色，用于检查慢性咽炎患者和健康人作为对照组的咽粘膜组织中幽门螺杆菌的定殖。结果：在对照组中，没有人发现咽部有幽门螺杆菌。相反，在50例慢性咽炎中，有19例（38.0％）的TDI-FP检测为幽门螺杆菌阳性，而4例（8％）的咽部有Giemsa染色为TDI-FP阳性。在50例咽炎病例中，有16例有胃病史，在这16例患者中，有11例（68.8％）通过TDI-FP分析被确定为咽部幽门螺杆菌阳性。 c2检验表明，此感染率比无胃病史的患者明显更高（P = 0.0007）。 Giemsa染色显示，有胃病史的患者中有3例（18.8％）在咽部感染了幽门螺杆菌，这比没有胃病史的患者（1例，这是明显的高）（P = 0.042）。 2.9％）。结论：健康人的咽部可能未检出幽门螺杆菌。慢性咽炎可能与幽门螺杆菌感染有关。有胃病史的患者的咽部幽门螺杆菌感染率要高于无胃病史的患者，这表明慢性咽炎可能与胃病史有关。

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