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首页> 外文期刊>World Journal of Gastroenterology >Prognostic factors of young patients with colon cancer after surgery.
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Prognostic factors of young patients with colon cancer after surgery.

机译：年轻结肠癌患者术后的预后因素。

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AIM: To investigate the prognostic factors of 96 young patients with colon cancer within a cancer center by univariate and multivariate analysis. METHODS: A total of 723 patients with colon cancer were treated surgically during a period of 10 years. Ninety six of them were 40 years old or younger.R0, R1 and R2 operations were performed in 69 (71.9%), 4(4.1%) and 23 patients(24%), respectively. Left hemicolectomy was performed in 43 patients, right hemicolectomy in 37 patients, transverse colon resection in 9 patients and low anterior resection in 7 patients. Cox multivariate regression analysis was performed to identify predictors of survival. RESULTS: The operation mortality was 0%, 54 patients died within 111 mo after operation due to occurrence or metastases of the tumor. Liver,lung and bone metastases occurred in 3, 1 and 5 patients, respectively.The mean survival time for all patients was 77.9 +/- 5.01 mo and the overall 3-,5- and 10- year survival rates were 66.68%, 58.14% and 46.54%, respectively. In the univariate survival analysis,patient age,type of operation, radical resection, blood transfusion, histological type, diameter of tumor,depth of tumor invasion, lymphatic invasion, distant metastases, liver metastases and TNM stage were found to be predictors of survival in young patients with colon cancer. In the Cox-regression analysis,blood transfusion and lymphatic invasion were determined as independent prognostic factors of survival. CONCLUSIONS: Age, type of operation, radical resection, blood transfusion, histological type, diameter of tumor,depth of tumor invasion, lymphatic invasion, distant metastasis and TNM stage are the predictors of survival in young patients with colon cancer after surgery.
机译：目的：通过单因素和多因素分析，调查96例癌症中心年轻结肠癌患者的预后。方法：总共723例结肠癌患者在10年内接受了手术治疗。其中的96名年龄在40岁以下，分别对69例（71.9％），4例（4.1％）和23例（24％）进行了R0，R1和R2手术。左半结肠切除术43例，右半结肠切除术37例，横结肠切除术9例，低位前切除术7例。进行Cox多变量回归分析以鉴定存活的预测因素。结果：手术死亡率为0％，其中54例因肿瘤的发生或转移而在术后111个月内死亡。肝，肺和骨转移分别发生在3、1和5例患者中。所有患者的平均生存时间为77.9 +/- 5.01 mo，总的3、5和10年生存率分别为66.68％，58.14 ％和46.54％。在单变量生存分析中，发现患者年龄，手术类型，根治性切除术，输血，组织学类型，肿瘤直径，肿瘤浸润深度，淋巴管浸润，远处转移灶，肝转移灶和TNM分期是预测生存率的因素。年轻的结肠癌患者。在Cox回归分析中，输血和淋巴管浸润被确定为生存的独立预后因素。结论：年龄，手术类型，根治性切除术，输血，组织学类型，肿瘤直径，肿瘤浸润深度，淋巴管浸润，远处转移和TNM分期是年轻结肠癌患者术后生存的预测指标。

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