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首页> 外文期刊>World Journal of Gastroenterology >Seroprevalence of Helicobacter pylori in dyspeptic patients and its relationship with HIV infection, ABO blood groups and life style in a university hospital, Northwest Ethiopia.
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Seroprevalence of Helicobacter pylori in dyspeptic patients and its relationship with HIV infection, ABO blood groups and life style in a university hospital, Northwest Ethiopia.

机译：消化不良患者的幽门螺杆菌血清阳性率及其与HIV感染，ABO血型和生活方式的关系，位于埃塞俄比亚西北部的一家大学医院。

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AIM: To determine the prevalence of Helicobacter pylori (H pylori) among dyspeptic patients and to assess the relationship between H pylori infection, blood group, HIV infection and life style of the patients. METHODS: In a hospital-based cross-sectional study, patients attending Outpatient Department of University of Gondar Hospital were enrolled. Socio-demographic information was collected using questionnaires. Serum was analyzed for anti-H pylori IgG antibodies using a commercial kit. HIV serostatus was determined by enzyme-linked immunosorbent assay (ELISA). Blood grouping was performed by slide agglutination tests. RESULTS: A total of 215 dyspeptic patients were included in the study. One hundred and sixteen patients (54%) were females and 99 (46%) were males. Anti-H pylori IgG antibodies were detected in sera of 184 (85.6%) patients. The prevalence was significantly higher in patients aged 50 years and above. Twenty point five percent of the patients were found to be seropositive for HIV. No significant association was found between sex, ABO blood groups, consumption of spicy diets, socio-economic status and seropositivity for H pylori. However, alcohol consumption was significantly associated with H pylori serology. CONCLUSION: The prevalence of H pylori infection is associated with a history of alcohol intake and older age. The effect of different diet, alcohol and socioeconomic status as risk factors for H pylori infection needs further study.
机译：目的：确定消化不良患者中幽门螺杆菌（H pylori）的患病率，并评估幽门螺杆菌感染，血型，HIV感染与患者生活方式之间的关系。方法：在一项基于医院的横断面研究中，纳入了Gondar大学医院门诊部的患者。使用调查表收集了社会人口统计学信息。使用市售试剂盒分析血清中的抗H幽门IgG抗体。通过酶联免疫吸附测定（ELISA）确定HIV血清状态。通过玻片凝集试验对血型进行分组。结果：总共215例消化不良患者被纳入研究。女性116例（54％），男性99例（46％）。在184名（85.6％）患者的血清中检测到抗H幽门IgG抗体。 50岁及以上的患者患病率明显更高。发现百分之二十五的患者对艾滋病毒呈血清反应阳性。在性别，ABO血型，辛辣饮食的消费，社会经济地位和幽门螺杆菌血清阳性之间没有发现显着关联。但是，饮酒与幽门螺杆菌血清学显着相关。结论：幽门螺杆菌感染的流行与饮酒史和高龄有关。不同饮食，酒精和社会经济状况作为幽门螺杆菌感染危险因素的影响需要进一步研究。

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