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首页> 外文期刊>World Journal of Gastroenterology >Spinal cord compression secondary to bone metastases from hepatocellular carcinoma.
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Spinal cord compression secondary to bone metastases from hepatocellular carcinoma.

机译：继发于肝细胞癌骨转移的脊髓压迫。

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摘要

Bone metastases are rare in primary hepatocellular carcinoma (HCC). Spinal cord compression (SCC) due to bone metastases occur commonly in patients with lung and breast carcinomas, and metastatic HCC is an unusual cause of SCC. Spinal cord compression is an oncologic emergency and treatment delays can lead to irreversible consequences. Thus, the awareness that SCC could be a potential complication of bone metastases due to HCC is of significance in initiation of early treatment that can improve the quality of life and survival of the patients, if diagnosed earlier. This paper describes four cases of primary HCC with varied manifestations of SCC due to bone metastases. The first patient presented primarily with the symptoms of bone pains corresponding to the bone metastases sites rather than symptoms of associated hepatic pathology and eventually developed SCC. The second patient, diagnosed as having HCC, developed extradural SCC leading to paraplegia during the course of illness, for which he underwentemergency laminectomy with posterior fixation. The third patient developed SCC soon after the primary diagnosis and had to undergo emergency laminectomy. Post laminectomy he had good neurological recovery. The Fourth patient presented primarily with radicular pains rather than frank paraplegia as the first manifestation of SCC.
机译：骨转移在原发性肝细胞癌（HCC）中很少见。由于骨转移引起的脊髓压迫（SCC）通常发生在肺癌和乳腺癌患者中，而转移性HCC是SCC的异常原因。脊髓压迫是一种肿瘤急症，治疗延迟可能导致不可逆转的后果。因此，认识到SCC可能是由于HCC引起的骨转移的潜在并发症，这对早期治疗的启动具有重要意义，如果可以更早诊断​​，它可以改善患者的生活质量和生存。本文描述了四例原发性肝癌，由于骨转移而伴有不同的SCC表现。第一例患者主要表现出与骨转移部位相对应的骨痛症状，而不是相关的肝病理学症状，并最终发展为SCC。第二名被诊断为肝癌的患者在病程中发展为硬膜外SCC，导致截瘫，为此他进行了后路椎板切除术并进行了后路固定术。第三名患者在初步诊断后不久就发展为SCC，必须接受急诊椎板切除术。椎板切除术后，他的神经恢复良好。第四例患者主要表现为神经根疼痛，而不是坦率的截瘫，这是SCC的最初表现。

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