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首页> 外文期刊>World Journal of Gastroenterology >Capsule (13)C-urea breath test for the diagnosis of Helicobacter pylori infection.
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Capsule (13)C-urea breath test for the diagnosis of Helicobacter pylori infection.

机译：胶囊（13）C-尿素呼气试验用于诊断幽门螺杆菌感染。

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摘要

AIM: To compare the accuracy of capsule (13)C-urea breath test (UBT) with conventional invasive methods for the diagnosis of Helicobacter pylori infection. METHODS: One hundred patients received CLO test, histological examination, culture and 100- or 50-mg capsule UBT for the diagnosis of H pylori infection. H pylori infection was defined as those with positive culture or positive results from both histology and CLO test. RESULTS: Both the sensitivity and specificity of the 100-mg capsule UBT (n = 50) were 100%. The sensitivity and specificity of the 50-mg capsule UBT (n = 50) were 96.4 and 100%, respectively. Taken together, the accuracy of capsule UBT (n = 100) was higher than that of CLO test, histology and culture (100% vs 92%, 91% and 89%, respectively; P = 0.035, 0.018 and 0.005, respectively). Our data showed that the optimal timing of sampling for 100- and 50-mg capsule UBT was 15-30 and 6-15 min, respectively. CONCLUSION: Capsule UBT has a higher accuracy compared with biopsy-based tests. It is an ideal method for the diagnosis of H pylori infection.
机译：目的：比较胶囊（13）C-尿素呼气试验（UBT）与常规侵入性方法诊断幽门螺杆菌感染的准确性。方法：100例患者接受了CLO测试，组织学检查，培养以及100或50 mg UBT胶囊用于诊断幽门螺杆菌感染。幽门螺杆菌感染定义为培养阳性或组织学和CLO试验结果均为阳性的感染。结果：100 mg胶囊UBT（n = 50）的敏感性和特异性均为100％。 50毫克胶囊UBT（n = 50）的敏感性和特异性分别为96.4和100％。两者合计，胶囊UBT的准确性（n = 100）高于CLO测试，组织学和培养的准确性（分别为100％对92％，91％和89％； P分别为0.035、0.018和0.005）。我们的数据显示，100 mg和50 mg胶囊UBT的最佳采样时间分别为15-30分钟和6-15分钟。结论：与基于活检的检查相比，UBT胶囊具有更高的准确性。它是诊断幽门螺杆菌感染的理想方法。

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