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首页> 外文期刊>World Journal of Gastroenterology >Sealing of the hepatic resection area using fibrin glue reduces significant amount of postoperative drain fluid.
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Sealing of the hepatic resection area using fibrin glue reduces significant amount of postoperative drain fluid.

机译：使用纤维蛋白胶密封肝切除区域可减少大量的术后引流液。

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AIM: To investigate whether the routine use of fibrin glue applied onto the hepatic resection area can diminish postoperative volume of bloody or biliary fluids drained via intraoperatively placed perihepatic tubes and can thus lower the complication rate. METHODS: Two groups of consecutive patients with a comparable spectrum of recent hepatic resections were compared: (1) 13 patients who underwent application of fibrin glue immediately after resection of liver parenchyma; (2) 12 patients who did not. Volumes of postoperative drainage fluid were determined in 4-h intervals through 24 h indicating the intervention caused bloody and biliary segregation. RESULTS: Through the first 8 h postoperatively, there was a tendency of higher amounts of fluids in patients with no additional application of fibrin glue while through the following intervals, a significant increase of drainage volumes was documented in comparison with the first two 4-h intervals, e.g., after 12 h, 149.6 mL +/-110 mL vs 63.2 mL +/-78 mL.Using fibrin glue, postoperative fluid amounts were significantly lower through the postoperative observation period of 24 h (851 mL +/-715 mL vs 315 mL +/-305 mL). CONCLUSION: For hepatic resections, the use of fibrin glue appears to be advantageous in terms of a significant decrease of surgically associated segregation of blood or bile out of the resection area. This might result in a better outcome.
机译：目的：探讨常规在肝切除区域使用纤维蛋白胶是否可以减少术后通过术中放置的肝周导管排出的血性或胆汁液的量，从而降低并发症发生率。方法：比较两组近期肝切除范围相似的连续患者：（1）13例肝实质切除后立即应用纤维蛋白胶的患者； （2）12例没有的患者。术后24小时内每隔4小时测定一次术后引流液的体积，表明该干预引起了血性和胆汁性隔离。结果：在术后的前8小时，没有额外应用纤维蛋白胶的患者有较高的液体量趋势，而在随后的时间间隔内，与前两个4小时相比，引流量明显增加间隔，例如12小时后为149.6 mL +/- 110 mL和63.2 mL +/- 78 mL。使用血纤蛋白胶在术后24 h观察期内的术后液体量显着降低（851 mL +/- 715 mL 315毫升+/- 305毫升）。结论：对于肝切除术，使用纤维蛋白胶似乎是有利的，因为这可以显着减少手术相关的血液或胆汁从切除区域的分离。这可能会导致更好的结果。

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