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Primary jejunoileal neoplasmas: a review of 60 cases

机译:原发性空肠空肠肿瘤:60例回顾

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AIM: Primary neoplasmas of the jejunum and ileum are infrequent and lack specific manifestations and inaccessibility of conventional endoscopy, so the diagnosis of these tumors are usually delayed. So far the data of primary jejunoileal neoplasmas is still scarce, especially in Chinese medical literature in English. There may be some differences among the Chinese and the westerners in jejunoileal neoplasmas. METHODS: A retrospective analysis was made on clinical findings and pathological types. RESULTS: Of the 60 patients with jejunal or ileal neoplasmas, the most frequent symptom was abdominal pain (57 %), followed by tarry stool (43 %) and hematochezia (10 %). Abdominal mass (40 %) was the most common finding on physical examination, followed by anemia and weight loss (35 %). 67 % of the jejunoileal neoplasms were located in the jejunum. Among the malignant neoplasmas (68 %), malignant stroma (47 %) was most common, while the benign stromoma (20 %) was the most common benign neoplasmas. Preoperatively, 40 patients (67 %) were diagnosed as small bowel neoplasmas, of which 34 were found by enteroclysis. Abdominal mass was shown by CT in 18 cases and by ultrasonography in 13. The mean duration of symptoms before diagnosis was 7 months. In 41 patients with malignant tumors, the duration of symptoms before diagnosis exceeded 12 months in 21 cases, lymphatic or distant metastases were found in 26 (63 %)cases during operation. An emergency laparotomy was performed in 4 patients (7 %) owing to intestinal obstruction or perforation. CONCLUSION: Primary jejunoileal neoplasmas in Chinese present some difference from Westerners on clinical features and histopathologic types. Enteroclysis remains the major relevant diagnostic procedure in this study, the misdiagnotic rate is high preoperatively due to failure of detection by conventional imaging procedures such as CT and inaccessibility of routine endoscopy. For the suspected patients, combined application of aforementioned procedures may facilitate early diagnosis. The wireless capsule endoscopy may improve the diagnostic rate of jejunoileal neoplasmas in the future.
机译:目的:空肠和回肠原发性肿瘤很少见,缺乏常规内窥镜检查的特异性表现和难以接近,因此这些肿瘤的诊断通常会延迟。到目前为止,原发性空肠赘生物的数据仍然很少,特别是在中医英文文献中。空肠赘生物在中国人和西方人之间可能有所不同。方法:对临床表现和病理类型进行回顾性分析。结果:在60例空肠或回肠赘生物患者中,最常见的症状是腹痛(57%),其次是柏油样便(43%)和便血(10%)。体检是最常见的腹部肿块(40%),其次是贫血和体重减轻(35%)。空肠肿瘤中有67%位于空肠中。在恶性肿瘤中(68%),恶性基质(47%)是最常见的,而良性基质瘤(20%)是最常见的良性肿瘤。术前40例(67%)被诊断为小肠肿瘤,其中34例通过肠溶发现。 CT检查显示腹部肿块18例,超声检查显示腹部肿块。诊断前平均症状持续时间为7个月。在41例恶性肿瘤患者中,有21例在诊断前的症状持续时间超过12个月,在手术期间发现26例(63%)病例发生淋巴或远处转移。由于肠梗阻或穿孔,对4例患者(7%)进行了紧急剖腹手术。结论:中国原发性空肠赘生物在临床特征和组织病理学类型上与西方人存在一定差异。肠分解术仍是本研究中主要的相关诊断程序,由于常规成像程序(例如CT)无法检测到和常规内窥镜无法进入,术前误诊率很高。对于可疑患者,结合使用上述程序可能有助于早期诊断。未来,无线胶囊内窥镜检查可提高空肠空肠肿瘤的诊断率。

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