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Modified technique for combined liver-small bowel transplantation in pigs

机译:猪肝小肠联合移植的改良技术

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AIM: As the conventional combined liver-small bowel transplantation is complicated with many postoperative complications, the aim of this study was to describe a modified technique for the combined liver-small bowel transplantation with preservation of the duodenum, partial head of pancreas and hepatic biliary system in pigs. METHODS: Composite liver/small bowel allotransplantations were undertaken in 30 long-white pigs. The graft included liver, about 3 to 4 m proximal jejunum, duodenum and partial pancreatic head. Vessels reconstructions included subhepatic vena cava-vena cava anastomosis, aorta-aorta anastomosis and portal-splenic vein anastomosis. RESULTS: Without immunosuppressive treatment, the median survival time of the animals was 6 days (2 to 12 days), and about 76.9% (20/26) of the animals survived for more than 4 days after operation. CONCLUSION: The modified technique is feasible and safe for the composite liver/small bowel transplantation with duodenum and pancreas preserved in pigs. And also this technique can simplify the operation and decrease possible postoperative complications.
机译:目的:由于常规的肝-小肠联合移植术复杂且术后并发症多,本研究的目的是描述一种改良的肝-小肠联合移植术,以保留十二指肠,胰腺部分头和肝胆猪系统。方法:对30只长白猪进行了肝脏/小肠同种异体移植。移植物包括肝脏,空肠近端3至4 m,十二指肠和部分胰头。血管重建包括肝下腔静脉-静脉腔吻合,主动脉-主动脉吻合和门静脉脾静脉吻合。结果:未经免疫抑制处理,动物的中位生存时间为6天(2至12天),约76.9%(20/26)的动物术后生存超过4天。结论:改良后的技术对猪十二指肠和胰脏的肝/小肠复合移植是可行且安全的。而且该技术可以简化手术并减少可能的术后并发症。

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