Methionine-dependence and combination chemotherapy on human gastric cancer cells in vitro

Wei-Xin Cao; Jing-Min Ou; Xu-Feng Fei

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Methionine-dependence and combination chemotherapy on human gastric cancer cells in vitro

机译：蛋氨酸依赖和联合化疗对人胃癌细胞的体外影响

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Conclusion: Human primary gastric cancer cells in vitro are Met-dependent; however, gastric mucosal cells have not shown the same characteristics. Met Hcy~+ environment may strengthen the killing effect of chemotherapy on human primary gastric cancer cells. Aim: To elucidate whether human primary gastric cancer And gastric mucosa epithelial cells in vitro can grow Normally in a methionine(Met)depleted environment, i.e. Met-dependence, and whether Met-depleting status can Enhance the killing effect of chemostherapy on gastric cancer Cells.

机译：结论：人原发性胃癌细胞在体外具有Met依赖性。然而，胃粘膜细胞没有显示出相同的特征。 Met Hcy〜+环境可能增强化学疗法对人原发性胃癌细胞的杀伤作用。目的：阐明人原发性胃癌和体外胃粘膜上皮细胞能否在蛋氨酸（Met）耗尽的环境（即Met依赖性）中正常生长，并且Met耗尽状态是否可以增强化学疗法对胃癌细胞的杀伤作用。

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来源
《World Journal of Gastroenterology》 |2002年第2期|p.230-232|共3页
作者
Wei-Xin Cao; Jing-Min Ou; Xu-Feng Fei;
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类消化系及腹部疾病;
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2. An in vitro study on the effects of the combination of salinomycin with cisplatin on human gastric cancer cells [J] . Zhang Zuwen, Zhao Jumei, Pang Qiuxia, Molecular medicine reports . 2017,第2aPta1期

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4. Efficacy of combination chemotherapy with docetaxel and irinotecan as first- or second-line treatment for advanced gastric cancer [C] . K. Sugiyama, A. Ishikawa, T. Watanabe International Gastric Cancer Congress . 2009

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5. Investigation of the effects of alpha-TEA, MSA and t-RES alone and in combination of human MDA-MB-435 breast cancer cells in vitro and in vivo. [D] . Snyder, Rachel Marie. 2006

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6. Methionine-dependence and combination chemotherapy on human gastric cancer cells in vitro [O] . Wei-Xin Cao, Jing-Min Ou, Xu-Feng Fei, 2002

机译：蛋氨酸依赖和联合化疗对人胃癌细胞的体外影响
7. Methionine-dependence and combination chemotherapy on human gastric cancer cellsin vitro [O] . Wei-Xin Cao, Jing-Min Ou, Xu-Feng Fei, 2002

机译：甲硫氨酸依赖性和组合化疗在体外人胃癌细胞

Methionine-dependence and combination chemotherapy on human gastric cancer cells in vitro

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