Effect of bowel rehabilitative therapy on structural adaptation of remnant small intestine: animal experiment

Xin Zhou; Yuan Xin Li; Ning Li

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Effect of bowel rehabilitative therapy on structural adaptation of remnant small intestine: animal experiment

机译：肠康复治疗对残余小肠结构适应的影响：动物实验

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AIM To investigate the individual and the combined effects of glutamine, dietary fiber, and growth hormone on the structural adaptation of the remnant small bowel. METHODS Forty-two adult male Sprague- Dawley rats underwent 85/100 mid-small bowel Resection and received total parenteral nutrition (TPN) support during the first three postoperational days. From the 4th postoperational day, animals were randomly assigned to receive 7 different treatments for 8 days: TPN_con group, receiving TPN and enteral 20 g.L~-1 glycine perfusion; TPN_Gln group, receiving TPN and enteral 20 g. L~-1 glutamine perfusion; Encon group, receiving enteral nutrition (EN) fortified with 20 g. L~-1 glutamine perfusion; Encon group, receiving enteral nutrition (EN) fortified with 20 g. L~-1 glycine; EN + Gln group, enteral nutrition fortified with 20 g.L~-1 glutamine; EN + Fib group, enteral nutrition and 2 g . d~-1 oral soybean fiber; EN+EH group, enteral nutrition and subcutaneous growth hormone (HG) (0.3 IU) injection twice daily; and ENint group, glutamine-enriched EN, oral soybean fiber, and subcutaneous GH injection.

机译：目的研究谷氨酰胺，膳食纤维和生长激素对残余小肠结构适应的个体及其联合作用。方法42只成年雄性Sprague-Dawley大鼠在手术后的前三天接受了85/100小肠中段切除术并接受了总肠胃外营养（TPN）支持。从术后第4天开始，将动物随机分为8天，分别接受7种不同的治疗：TPN_con组，接受TPN和肠内20 g.L〜-1甘氨酸灌流。 TPN_Gln组，接受TPN和肠溶20克。 L〜-1谷氨酰胺灌注; Encon组，接受强化的20 g肠内营养（EN）。 L〜-1谷氨酰胺灌注; Encon组，接受强化的20 g肠内营养（EN）。 L〜-1甘氨酸; EN + Gln组，肠内营养强化20 g.L〜-1谷氨酰胺； EN + Fib组，肠内营养2 g。 d〜-1口服大豆纤维； EN + EH组，每天两次肠内营养和皮下生长激素（HG）（0.3 IU）注射； ENint组，富含谷氨酰胺的EN，口服大豆纤维和皮下GH注射。

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来源
《World Journal of Gastroenterology》 |2001年第1期|p.66-73|共8页
作者
Xin Zhou; Yuan Xin Li; Ning Li;
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类消化系及腹部疾病;
关键词
Short bowel syndrome; intestinal mucosa; somatotropin;

机译：短肠综合征;肠粘膜生长激素;

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6. Effect of bowel rehabilitative therapy on structural adaptation of remnant small intestine: animal experiment [O] . Xin Zhou, Yuan Xin Li, Ning Li, 2001

机译：肠康复治疗对残余小肠结构适应的影响：动物实验
7. Effect of bowel rehabilitative therapy on structural adaptation of remnant small intestine: animal experiment [O] . Xin Zhou 2001

机译：肠康复治疗对残余小肠结构适应的影响：动物实验

Effect of bowel rehabilitative therapy on structural adaptation of remnant small intestine: animal experiment

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