Growth inhibition and apoptosis induction of Sulindac on Human gastric cancer cells

Yun-Lin Wu; Xue-Jun Zhang; Sheng-Nian Wang

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Growth inhibition and apoptosis induction of Sulindac on Human gastric cancer cells

机译：舒林酸对人胃癌细胞的生长抑制和凋亡诱导

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Conclusion: Sulindac could inhibit the growth of gastric cancer cells and HCC cells effectively in vitro by apoptosis induction, which was associated with regression of COX-2 and Bcl-1 expression. The growth inhibitor and apoptosis of HCC cells were greater than that of human gastric cancer cells. the different effects of apoptosis in gastric cancer cells may be related to the differentiation of the cells. Aim: To evaluate the effects of sulindac in inducing growth Inhibition and apoptosis of human gastric cancer cells in Comparison with human hepatocellular carcinoma(HCC) Cells.

机译：结论：舒林酸可通过凋亡诱导有效抑制胃癌细胞和肝癌细胞的生长，这与COX-2和Bcl-1的表达降低有关。 HCC细胞的生长抑制剂和细胞凋亡大于人胃癌细胞。胃癌细胞凋亡的不同作用可能与细胞的分化有关。目的：与人肝癌细胞（HCC）相比，评估舒林酸对人胃癌细胞的生长抑制和凋亡的影响。

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来源
《World Journal of Gastroenterology》 |2001年第6期|p.796-800|共5页
作者
Yun-Lin Wu; Xue-Jun Zhang; Sheng-Nian Wang;
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作者单位

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类消化系及腹部疾病;
关键词
sulindac; apoptosis; gastric cancer; HCC;

机译：舒林酸细胞凋亡胃癌;肝癌;

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6. Growth inhibition and apoptosis induction of Sulindac on Human gastric cancer cells [O] . Yun-Lin Wu, Bo Sun, Xue-Jun Zhang, 2001

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7. Growth inhibition and apoptosis induction of Sulindac on Human gastric cancer cells [O] . Yun-Lin Wu 2001

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Growth inhibition and apoptosis induction of Sulindac on Human gastric cancer cells

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