Localization of HCV RNA and capsid protein in human hepatocellular carcinoma

Dai YM; Shou ZP; Ni CR

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Localization of HCV RNA and capsid protein in human hepatocellular carcinoma

机译：HCV RNA和衣壳蛋白在人肝细胞癌中的定位

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The relation of HCV to hepatocytic carcinoma (HCC) has been emphasized recently in low HBV infection countries and regions. The distribution patterns of HCV in liver tissues are not well understood although studies on HCV infection in blood and hepatocytes have been conducted by PCR. In this study, 42 liver cancers and Surrounding liver tissues were detected for HCV RNA and HCAg using photosensitive biotin-labeled HCV cDNA probe and Immuno-gold-siver stain (IGSS) method.

机译：在低HBV感染的国家和地区，最近已强调了HCV与肝细胞癌的关系。尽管已经通过PCR对血液和肝细胞中的HCV感染进行了研究，但对肝脏组织中HCV的分布方式还没有很好的了解。在这项研究中，使用光敏生物素标记的HCV cDNA探针和免疫金-绿色染色剂（IGSS）方法检测了42例肝癌和周围肝组织中的HCV RNA和HCAg。

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来源
《World Journal of Gastroenterology》 |2000年第1期|p.136-137|共2页
作者
Dai YM; Shou ZP; Ni CR;
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类消化系及腹部疾病;
关键词
hepatitis C virus; liver neoplasma; carcinoma;

机译：丙型肝炎病毒;肝肿瘤癌;

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2. Expression of functional receptors for human C5a anaphylatoxin (CD88) on the human hepatocellular carcinoma cell line HepG2. Stimulation of acute-phase protein-specific mRNA and protein synthesis by human C5a anaphylatoxin. [J] . Buchner RR, Hugli TE, Ember JA, The Journal of Immunology: Official Journal of the American Association of Immunologists . 1995,第1期

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3. Differential Expression of Glypican-3 and Insulin–Like Growth Factor-II mRNAs and Alpha-fetoprotein and Ki-67 markers in Liver Tissues of HCV related Hepatocellular carcinoma in Egyptian Patients [J] . Mohamed Ali Saber, Samah Abdel Hafiz, Fatma EL-Zahraa Mohamed Khorshed, Asian Pacific Journal of Cancer Prevention . 2017,第1期

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4. Correlation between Clinicopathology and Immunolocalization of Heat Shock Protein 72 and Glycoprotein 96 in Human Hepatocellular Carcinomas [C] . XiaoPing Wang, HuanPing Lin, QiaoXia Wang International Conference on Material Engineering, Chemistry, Bioinformatics . 2011

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5. Regulation of the HCV RNA-dependent RNA polymerase NS5B by the HCV capsid protein and characterization of the NS5B juxtamembrane linker [D] . Wen, Yahong. 2014

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6. Localization of HCV RNA and capsid protein in human hepatocellular carcinoma [O] . Yi-Min Dai, Zhi-Ping Shou, Can-Rong Ni, 2000

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7. HCV Proteins Modulate the Host Cell miRNA Expression Contributing to Hepatitis C Pathogenesis and Hepatocellular Carcinoma Development [O] . Devis Pascut, Minh Hoang, Nhu N. Q. Nguyen, 2021

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Localization of HCV RNA and capsid protein in human hepatocellular carcinoma

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