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首页> 外文期刊>Bulletin of the National Research Centre >Protective Role of Green Tea and Panax Ginseng in Cancer-Promoting Diets: A Sub-chronic Study on the Male Albino Rats
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Protective Role of Green Tea and Panax Ginseng in Cancer-Promoting Diets: A Sub-chronic Study on the Male Albino Rats

机译：绿茶和人参在促癌饮食中的保护作用：对雄性白化病大鼠的亚慢性研究

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摘要

Effect of over-heated meat and fish (OHM and OHF) on the nutritional, biochemical, histological and haematological parameters as well as chromosomal aberrations and sperm abnormalities was investigated in male albino rats. Animals were divided into two main groups: meat group and fish group. Each group was divided into six subgroups: G-Ⅰ, was fed the basal diet contained more than 12% dry frozen meat, G-Ⅱ and G-Ⅲ were fed the basal diet of G-Ⅰ plus 5% of green tea and panax ginseng, respectively, G-Ⅳ was fed the basal diet that contained more than 12% OHM, and G-Ⅴ and G-Ⅵ were fed the diet of G-Ⅳ plus 5% of green tea and panax ginseng, respectively. The same classification was done for the fish-group. It was found that the terminal body weight was increased non-significantly in all rat groups until the fifth week, and then decreased non-significantly until the end of the experimental period (8 weeks). No effect on serum cholesterol, triglycerides, total lipids and glucose levels was found . On the other hand, significant values of both hepatic and renal function parameters were obtained among OHM/OHF-treated animals. Numerous histological alterations, particularly in the liver, were also observed. Furthermore, anaemia, leukocytosis, neutrophilia, lymphocytosis and monocytosis were seen. Moreover, chromosomes and sperms were adversely affected in such animals fed diets contained OHM/OHF. The protective action of green tea and panax ginseng was observed in all biochemical, histological and haematological parameters. In addition, improvement in chromosomal aberration and sperm abnormalities was also noticed.
机译：研究了过热的肉和鱼（OHM和OHF）对雄性白化病大鼠营养，生化，组织学和血液学参数以及染色体畸变和精子异常的影响。将动物分为两个主要组：肉组和鱼组。每组分为六个亚组：G-Ⅰ，饲喂干冷冻肉含量超过12％的基础饮食；G-Ⅱ和G-Ⅲ，饲喂G-Ⅰ的基础饮食，再加上5％的绿茶和人参人参，分别给G-Ⅳ和O-含量超过12％的基础饮食喂食，G-Ⅴ和G-Ⅵ分别喂食G-Ⅳ加5％的绿茶和人参。对鱼群进行了相同的分类。发现在所有大鼠组中，终末体重直到第5周都没有显着增加，然后直到实验期结束（8周）才显着降低。未发现对血清胆固醇，甘油三酸酯，总脂质和葡萄糖水平有影响。另一方面，在OHM / OHF治疗的动物中，肝和肾功能参数均获得了显着值。还观察到许多组织学改变，特别是在肝脏中。此外，还观察到贫血，白细胞增多，中性粒细胞增多，淋巴细胞增多和单核细胞增多。此外，喂食含有OHM / OHF的这类动物的染色体和精子受到不利影响。在所有生化，组织学和血液学参数中均观察到绿茶和人参的保护作用。另外，还注意到染色体畸变和精子异常的改善。

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