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首页> 外文期刊>Cancer Cell International >Promoter methylation status of the tumor suppressor gene SOX11 is associated with cell growth and invasion in nasopharyngeal carcinoma
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Promoter methylation status of the tumor suppressor gene SOX11 is associated with cell growth and invasion in nasopharyngeal carcinoma

机译:抑癌基因SOX11的启动子甲基化状态与鼻咽癌的细胞生长和侵袭有关

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摘要

Background The transcription factor SOX11 is one of members of the SRY box-containing (SOX) family emerging as important transcriptional regulators. In recent years, up-regulation of SOX11 has been detected in various types of solid tumors. In this study, the effects of promoter methylation of the SOX11 gene on SOX11 expression and cell growth and invasion of nasopharyngeal carcinoma were investigated.
机译:背景技术转录因子SOX11是包含SRY盒(SOX)的家族之一,成为重要的转录调节因子。近年来,已在各种类型的实体瘤中检测到SOX11的上调。在这项研究中,研究了SOX11基因的启动子甲基化对鼻咽癌中SOX11表达以及细胞生长和侵袭的影响。

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