Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis

Katie R Hagen; Xiangbin Zeng; Mi-Young Lee; Shannon Tucker Kahn; Mary Kathryn Harrison Pitner; Sandra S Zaky; Yuan Liu; Ruth M O’Regan; Xingming Deng; Harold I Saavedra

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Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis

机译：沉默CDK4通过促进细胞凋亡对乳腺癌细胞产生放射敏感性

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Background The discovery of molecular markers associated with various breast cancer subtypes has greatly improved the treatment and outcome of breast cancer patients. Unfortunately, breast cancer cells acquire resistance to various therapies. Mounting evidence suggests that resistance is rooted in the deregulation of the G1 phase regulatory machinery.

机译：背景技术与各种乳腺癌亚型相关的分子标记的发现大大改善了乳腺癌患者的治疗和结局。不幸的是，乳腺癌细胞获得了对各种疗法的抗性。越来越多的证据表明，抵抗力根源于G1相调控机制的放松。

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《Cell Division》 |2013年第1期|1-17|共17页
作者
Katie R Hagen; Xiangbin Zeng; Mi-Young Lee; Shannon Tucker Kahn; Mary Kathryn Harrison Pitner; Sandra S Zaky; Yuan Liu; Ruth M O’Regan; Xingming Deng; Harold I Saavedra;
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正文语种 eng
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CDK4 CDK2 Radiation Bad Radioresistance Radiosensitization Breast cancer Apoptosis;

机译：CDK4 CDK2辐射不良放射抵抗放射敏感性乳腺癌细胞凋亡;

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1. Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis [J] . Katie R Hagen, Xiangbin Zeng, Mi-Young Lee, Cell Division . 2013,第1期

机译：沉默CDK4通过促进凋亡使乳腺癌细胞放射增敏
2. Silencing survivin gene expression promotes apoptosis of human breast cancer cells through a caspase-independent pathway. [J] . Croci DO, Cogno IS, Vittar NB, Journal of cellular biochemistry. . 2008,第2期

机译：沉默survivin基因表达可通过不依赖胱天蛋白酶的途径促进人乳腺癌细胞的凋亡。
3. Silencing human epidermal growth factor receptor‐3 radiosensitizes human luminal A breast cancer cells [J] . Guofeng He, Xiaoke Di, Jingjing Yan, Cancer science. . 2018,第12期

机译：沉默人类表皮生长因子受体-3使人类管腔A乳腺癌细胞放射增敏
4. Autophagy Inhibition Promotes HDACI-induced Apoptosis in MCF-7 Breast Cancer Cells [C] . Shimiao Wang, Xiaohui Li, Zhilong Xiu Chinese International Peptide Symposium . 2013

机译：自噬抑制促进HDACI诱导的MCF-7乳腺癌细胞凋亡
5. DLX4 homeoprotein promotes PI3K/Akt anti-apoptosis pathway in ER negative breast cancer cells through upregulation of VEGFA. [D] . Wu, Weiwei. 2010

机译：DLX4同源蛋白通过上调VEGFA促进ER阴性乳腺癌细胞中的PI3K / Akt抗凋亡途径。
6. Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis [O] . Katie R Hagen, Xiangbin Zeng, Mi-Young Lee, 2013

机译：沉默CDK4通过促进细胞凋亡对乳腺癌细胞产生放射敏感性
7. Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis [O] . 2013

机译：沉默CDK4通过促进细胞凋亡对乳腺癌细胞产生放射敏感性
8. Role of TMS1 Silencing in the Resistance of Breast Cancer Cells to Apoptosis [R] . Parsons, M. J. , Vertino, P. M. 2006

机译：Tms1沉默在乳腺癌细胞凋亡中的作用

Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis

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