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首页> 外文期刊>Cell Research >Adiponectin as a negative regulator in obesity-related mammary carcinogenesis
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Adiponectin as a negative regulator in obesity-related mammary carcinogenesis

机译：脂联素作为肥胖相关乳癌发生中的负调节剂

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摘要

The prevalence of obesity and its associated diseases has posed a huge healthcare impact on our society. Obesity is a maj or risk factor for many serious medical conditions, such as metabolic syndrome, Type 2 Diabetes and cardiovascular disorders etc. In addition, the close association of obesity with cancers has attracted significant attentions. Several obesity-related cancers, including breast, prostate, endo-metrium, colon and gallbladder cancer, have a hormonal basis and are life style-related. Breast cancer is the most frequent cancer and the second leading cause of cancer death among women. Excess adiposity over the pre- and post-menopausal years is an independent risk factor for the development of breast cancer, and is also associated with late-stage disease and poor prognosis.
机译：肥胖及其相关疾病的流行对我们的社会造成了巨大的医疗影响。肥胖是许多严重医学疾病的主要因素或危险因素，例如代谢综合征，2型糖尿病和心血管疾病等。此外，肥胖与癌症的密切关系引起了广泛关注。几种与肥胖有关的癌症，包括乳腺癌，前列腺癌，子宫内膜癌，结肠癌和胆囊癌，都具有激素基础，并且与生活方式有关。乳腺癌是女性中最常见的癌症，也是癌症死亡的第二大主要原因。绝经前后肥胖过多是乳腺癌发展的独立危险因素，也与晚期疾病和不良预后有关。

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  • 来源
    《Cell Research》 |2007年第4期|p.280-282|共3页
  • 作者

    Yu Wang; Karen SL Lam; Aimin Xu;

  • 作者单位

    Genome Research Center, Hormone and Healthy Aging, University of Hong Kong, Hong Kong SAR, China;

  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 细胞生物学;
  • 关键词

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