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Central diabetes insipidus and adipsia due to astrocytoma: diagnosis and management

机译：星状细胞瘤导致的中枢性尿崩症和脂肪缺乏症：诊断和治疗

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摘要

Adipsia and/or diabetes insipidus is rarely a direct complication of astrocytoma. We report a young man with recurrence of anaplastic astrocytoma who presented as severe hypernatremia. This case highlights key diagnostic and therapeutic challenges: (1) the interpretation of the response to exogenous vasopressin in a patient with steroid-induced hyperglycemia and (2) the potential risk of brain edema and herniation if excess water is prescribed along with vasopressin supplementation. The patient was successfully managed with prescribed fluid replacement, daily weights, and regular electrolyte monitoring but no exogenous vasopressin for 8 months until he succumbed to his tumor.
机译：肥胖和/或尿崩症很少是星形细胞瘤的直接并发症。我们报告了一个年轻人，间变性星形细胞瘤复发，表现为严重的高钠血症。该病例突出了关键的诊断和治疗挑战：（1）类固醇诱导的高血糖患者对外源性加压素反应的解释，以及（2）如果补充了加压素并补充了过量的水，则可能导致脑水肿和疝气。该患者已成功接受处方液体补充，每日体重和定期电解质监测的治疗，但直到他死于肿瘤之前8个月都没有外源性加压素。

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  • 来源
    《CEN Case Reports》 |2013年第1期|11-16|共6页
  • 作者

    Imad Modawi; Geoffrey R. Barger; Noreen F. Rossi;

  • 作者单位

    Department of Internal Medicine Wayne State University School of Medicine">(1);

    John D. Dingell VA Medical Center">(5);

    Department of Neurology Wayne State University School of Medicine">(2);

    Karmanos Cancer Institute Wayne State University School of Medicine">(4);

    Department of Internal Medicine Wayne State University School of Medicine">(1);

    Department of Physiology Wayne State University School of Medicine">(3);

    John D. Dingell VA Medical Center">(5);

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Astrocytoma; Hypernatremia; Hypodipsia; Vasopressin;

    机译：星状细胞瘤高钠血症;催眠;加压素;

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