Acute kidney injury due to acyclovir

Cigdem Yildiz; Yasemin Ozsurekci; Safak Gucer; Ali Bulent Cengiz; Rezan Topaloglu

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Acute kidney injury due to acyclovir

机译：阿昔洛韦引起的急性肾脏损伤

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Acyclovir is an antiviral agent widely used in herpetic infections in children. Although acyclovir is generally well tolerated, severe nephrotoxicity has been reported in some cases. In this report, we present a 16-year-old girl who developed acute renal failure due to acyclovir treatment and who needed repetitive hemodialysis. Renal biopsy was performed in order to confirm the diagnosis. A diagnosis of drug-related acute tubulointerstitial nephritis with focal tubular necrosis was made.

机译：阿昔洛韦是广泛用于儿童疱疹感染的抗病毒药物。尽管一般对阿昔洛韦的耐受性良好，但在某些情况下已报道严重的肾毒性。在本报告中，我们介绍了一个因阿昔洛韦治疗而导致急性肾衰竭的16岁女孩，需要重复进行血液透析。为了确定诊断，进行了肾脏活检。诊断为药物相关的急性肾小管间质性肾炎伴局灶性肾小管坏死。

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来源
《CEN Case Reports》 |2013年第1期|38-40|共3页
作者
Cigdem Yildiz; Yasemin Ozsurekci; Safak Gucer; Ali Bulent Cengiz; Rezan Topaloglu;
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作者单位

Department of Pediatric Nephrology and Rheumatology Hacettepe University Faculty of Medicine">(1);

Department of Pediatric Infectious Diseases Hacettepe University Faculty of Medicine">(2);

Department of Pediatric Pathology Hacettepe University Faculty of Medicine">(3);

Department of Pediatric Infectious Diseases Hacettepe University Faculty of Medicine">(2);

Department of Pediatric Nephrology and Rheumatology Hacettepe University Faculty of Medicine">(1);

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原文格式 PDF
正文语种 eng
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关键词
Acyclovir; Acute renal failure; Repetitive hemodialysis;

机译：阿昔洛韦;急性肾功能衰竭;重复性血液透析;

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1. Acute Kidney Injury During Treatment with Intravenous Acyclovir for Suspected or Confirmed Neonatal Herpes Simplex Virus Infection [J] . The Journal of pediatrics . 2020,第期

机译：急性肾损伤治疗静脉内Acyclovir疑似或证实新生儿疱疹单纯疱疹病毒感染
2. Association between Concomitant Use of Acyclovir or Valacyclovir with NSAIDs and an Increased Risk of Acute Kidney Injury: Data Mining of FDA Adverse Event Reporting System [J] . Yue Zhihua, Shi Jinhai, Li Haona, Biological & pharmaceutical bulletin . 2018,第2期

机译：伴随acyclovir或valacyclovir与NSAID的关系和急性肾损伤的风险增加：FDA不良事件报告系统的数据挖掘
3. Acute kidney injury due to acyclovir: A case report [J] . H.L. Yen, S.C. Tsai Journal of the Neurological Sciences: Official Bulletin of the World Federation of Neurology . 2017,第期

机译：Acyclovir引起的急性肾脏损伤：案例报告
4. Diagnosis of Acute Kidney Injury Using Functional and Injury Biomarkers: Workgroup Statements from the Tenth Acute Dialysis Quality Initiative Consensus Conference [C] . Peter A. McCullough, Andrew D. Shaw, Michael Haase, Conference on Biomarkers in AKI (Acute Kidney Injury) . 2013

机译：使用功能和损伤生物标志物的诊断急性肾损伤：第十个急性透析质量倡议协商会议的工作组陈述
5. Outpatient Acute Kidney Injury Increases Risk of Mortality and Chronic Kidney Disease [D] . Leither, Maxwell. 2017

机译：门诊急性肾损伤增加了死亡率和慢性肾病的风险
6. The incidence risk factors and clinical outcomes of acute kidney injury (staged using the RIFLE classification) associated with intravenous acyclovir administration [O] . Eun Ju Lee, Ha Nee Jang, Hyun Seop Cho, 2018

机译：静脉给予阿昔洛韦相关的急性肾损伤（使用RIFLE分类法）的发生率危险因素和临床结局
7. Association between Concomitant Use of Acyclovir or Valacyclovir with NSAIDs and an Increased Risk of Acute Kidney Injury: Data Mining of FDA Adverse Event Reporting System [O] . Zhihua Yue, Jinhai Shi, Haona Li, 2018

机译：伴随acyclovir或valacyclovir与NSAID的关系和急性肾损伤的风险增加：FDA不良事件报告系统的数据挖掘

Acute kidney injury due to acyclovir

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