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首页> 外文期刊>Chemical Senses >Comparison between Odor Thresholds for Phenyl Ethyl Alcohol and Butanol
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Comparison between Odor Thresholds for Phenyl Ethyl Alcohol and Butanol

机译：苯乙醇和丁醇气味阈值的比较

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摘要

Aim of the study was to compare results of odor threshold test using different numbers of dilution steps, separately for butanol and phenyl ethyl alcohol (PEA). Methods: A total of 116 subjects participated (29 patients with olfactory dysfunction and 87 normosmic subjects). The olfactory threshold for butanol and PEA was examined with 8 (wide step method) and 16 (narrow step method) dilutions. With a delay of about 1 week, all 4 tests were repeated. Results: Test time was shortened by approximately 2 min (25%) for patients when using the wide step method. Butanol and PEA thresholds were not significantly different; in addition, a significant correlation was found between thresholds for the 2 odors (r = 0.60, P 0.001). Threshold test with both odorants as well as with wide or narrow step method provided satisfying reproducibility (test–retest reliability: r = 0.80–0.84, P 0.001). Patients with olfactory dysfunction could be clearly separated from normosmic subjects using all 4 different tests. Discussion: The results indicate that threshold testing with PEA is an alternative to butanol. The wide step method provided similar results as the narrow step method but required less time.
机译：该研究的目的是比较分别使用丁醇和苯乙醇（PEA）进行不同稀释步骤的气味阈值测试的结果。方法：共有116名受试者（29名嗅觉障碍和87名正常受试者）参加。用8种（宽步法）和16种（窄步法）稀释液检测丁醇和PEA的嗅觉阈值。延迟约1周，重复所有4个测试。结果：使用宽步法时，患者的测试时间缩短了约2分钟（25％）。丁醇和PEA阈值无明显差异；此外，在两种气味的阈值之间发现显着相关性（r = 0.60，P <0.001）。两种气味剂以及宽步法或窄步法的阈值测试均提供了令人满意的重现性（重测信度：r = 0.80–0.84，P <0.001）。使用所有4种不同的测试，可以将嗅觉障碍的患者与正常受试者明确分开。讨论：结果表明，使用PEA进行阈值测试可以替代丁醇。宽步法提供的结果与窄步法相似，但所需时间更少。

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