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首页> 外文期刊>Chemosphere >The role of vitamin C as antioxidant in protection of biochemical and haematological stress induced by chlorpyrifos in freshwater fish Clarias batrachus
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The role of vitamin C as antioxidant in protection of biochemical and haematological stress induced by chlorpyrifos in freshwater fish Clarias batrachus

机译：维生素C作为抗氧化剂在毒死rif对淡水鱼枝ba的生化和血液学应激保护中的作用

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摘要

The study was conducted to explore the modulatory effects of chlorpyrifos and protective role of vitamin C in tissues of Clarias batrachus. Treatments include El group (basal diet plus 1.65 mg L-1 CPF) and E-2 group (basal diet + 200 mg kg body weight vitamin C and 1.65 mg L-1 CPF) along with a control group of fishes (fed on basal diet only). After 1, 7, 15, and 30 d of treatment, fish tissues (brain, blood and liver) were used for the estimation of growth, biochemical and haematological parameters. The results of E-1 group indicated significantly lower weight gain and survival rate. Brain AChE activity was inhibited. The RBC, Hb, respiratory burst activity, total protein and HSI were also reduced whereas WBC count, plasma glucose and haematocrit were elevated. In contrast, liver glycogen content, lactate dehydrogenase, alkaline and acid phosphatase activities were inhibited and malate dehydrogenase, aspartate, alanine amino transferase were enhanced. The E2 group of fish exhibited significant improvement in growth, survival, haematological indices, brain AChE, liver glycogen and oxidative enzyme activity. The findings support that dietary vitamin C supplementation might be helpful in abrogation of chlorpyrifos toxicity and improves growth, survival, biochemical and haematological conditions in fishes. (C) 2015 Elsevier Ltd. All rights reserved.
机译：进行该研究以探讨毒死rif的调节作用和维生素C在非洲胡子Cl组织中的保护作用。治疗方法包括El组（基础饮食加1.65 mg L-1 CPF）和E-2组（基础饮食+ 200 mg kg体重维生素C和1.65 mg L-1 CPF）以及对照组鱼（基础饮食）仅饮食）。处理1、7、15和30天后，将鱼的组织（脑，血液和肝脏）用于生长，生化和血液学参数的估计。 E-1组的结果表明体重增加和存活率显着降低。脑AChE活性受到抑制。 RBC，Hb，呼吸爆发活性，总蛋白和HSI也降低，而WBC计数，血浆葡萄糖和血细胞比容升高。相反，肝糖原含量，乳酸脱氢酶，碱性和酸性磷酸酶活性受到抑制，苹果酸脱氢酶，天冬氨酸，丙氨酸氨基转移酶得到增强。 E2组鱼类在生长，存活，血液学指标，脑AChE，肝糖原和氧化酶活性方面显示出显着改善。这些发现支持饮食中补充维生素C可能有助于消除毒死rif的毒性，并改善鱼类的生长，存活，生化和血液学状况。 （C）2015 Elsevier Ltd.保留所有权利。

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  • 来源
    《Chemosphere》 |2015年第8期|172-178|共7页
  • 作者

    Narra Madhusudan Reddy; Rajender Kodimyala; Reddy R. Rudra; Rao J. Venkateswara; Begum Ghousia;

  • 作者单位

    Osmania Univ, Coll Sci, Dept Zool, Hyderabad 500007, Andhra Pradesh, India;

    Osmania Univ, Coll Sci, Dept Zool, Hyderabad 500007, Andhra Pradesh, India;

    Osmania Univ, Coll Sci, Dept Zool, Hyderabad 500007, Andhra Pradesh, India;

    Indian Inst Chem Technol, CSIR, Div Biol, Toxicol Unit, Hyderabad 500007, Andhra Pradesh, India;

    Indian Inst Chem Technol, CSIR, Div Biol, Toxicol Unit, Hyderabad 500007, Andhra Pradesh, India;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Clarias batrachus; Pesticide; Vitamin C; Haematology; Biochemistry;

    机译：鼠尾草;农药;维生素C;血液学;生化;

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