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首页> 外文期刊>Chemosphere >Presence of organochlorine pesticides in breast milk samples from Colombian women
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Presence of organochlorine pesticides in breast milk samples from Colombian women

机译：哥伦比亚妇女的母乳样品中存在有机氯农药

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摘要

The presence of Organochlorine Pesticides (OCPs) in biological and environmental samples has been studied for decades in many countries. Nonetheless, studies in Latin American countries like Colombia have been scarce. Determining the presence of OCPs in breast milk will be of relevance to assess exposures, potential health risks, and for surveillance among Latin American populations. Thirty-two breast-feeding mothers were selected to voluntarily participate in the study. Breast milk samples were analyzed for 10 OCPs (α-, β-, γ-, δ-HCH, Heptachlor, α-, γ-Chlordane, 4,4' DDT, 4,4' DDE, 4,4' DDD). Milk samples were analyzed using liquid-liquid extraction, followed by sulfuric acid cleanup, and quantified using GC/μECD. Results were confirmed by GC/MS. OCPs concentrations were normalized using fat content. In all but one sample, 4,4' DDE was quantified in concentrations ranging between <17 and 14948 ng g~（-1） (ng of OCP per g of lipids), with a mean value of 203 ng g~（-1）. One woman had 4,4' DDE concentrations that were orders of magnitude above the average concentrations observed worldwide. Concentrations of 4,4' DDE in a second breast milk sample collected in a different time period of lactation from a sub-group of 13 women from the original participants, showed no statistically significant difference with the concentrations found in the first sample. Based on the results obtained from the Persistent Organic Pollutants Global Monitoring Plan report of 2009 of the Stockholm Convention, Colombia ranks fourth from bottom to top in terms of 4,4' DDE average concentrations.
机译：许多国家已经研究了生物和环境样品中有机氯农药（OCP）的存在。尽管如此，在像哥伦比亚这样的拉丁美洲国家的研究却很少。确定母乳中OCP的存在与评估暴露量，潜在的健康风险以及对拉丁美洲人群进行监测有关。选择了32名母乳喂养母亲自愿参加这项研究。分析母乳样品中的10种OCP（α-，β-，γ-，δ-HCH，七氯，α-，γ-氯丹，4,4'DDT，4,4'DDE，4,4'DDD）。使用液-液萃取分析牛奶样品，然后进行硫酸净化，并使用GC /μECD进行定量。结果通过GC / MS确认。使用脂肪含量将OCPs浓度标准化。在除一个样品外的所有样品中，定量的4,4'DDE浓度范围在<17至14948 ng g〜（-1）（每克脂质中的OCP ng），平均值为203 ng g〜（-1）。 ）。一名妇女的4,4'DDE浓度比全世界观察到的平均浓度高几个数量级。在不同泌乳时间段从原始参与者的13个妇女亚组中收集的第二份母乳样品中的4,4'DDE浓度与第一个样品中发现的浓度无统计学差异。根据《斯德哥尔摩公约》 2009年《持久性有机污染物全球监测计划》报告获得的结果，哥伦比亚在4,4'DDE平均浓度方面排名从下至上排名第四。

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  • 来源
    《Chemosphere》 |2013年第6期|733-739|共7页
  • 作者

    Ximena Rojas-Squella; Laura Santos; Wolfram Baumann; Diana Landaeta; Adriana Jaimes; Juan C. Correa; Olga L. Sarmiento; Juan Pablo Ramos-Bonilla;

  • 作者单位

    Department of Civil and Environmental Engineering, School of Engineering, Universidad de los Andes, Bogotd, Colombia;

    Department of Civil and Environmental Engineering, School of Engineering, Universidad de los Andes, Bogotd, Colombia;

    Department of Chemistry, School of Science, Universidad de los Andes, Bogotd, Colombia;

    Community Health Division, Fundacion Santa Fe de Bogotd, Bogota, Colombia;

    Department of Civil and Environmental Engineering, School of Engineering, Universidad de los Andes, Bogotd, Colombia;

    Community Health Division, Fundacion Santa Fe de Bogotd, Bogota, Colombia;

    School of Medicine, Universidad de los Andes, Bogota, Colombia;

    Department of Civil and Environmental Engineering, School of Engineering, Universidad de los Andes, Bogotd, Colombia;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    breast milk; organochlorine pesticides; biomarker of exposure; colombia;

    机译：母乳有机氯农药;暴露的生物标志物;哥伦比亚;

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