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首页> 外文期刊>Chemosphere >Concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and dioxin-like polychlorinated biphenyls in blood collected from 195 pregnant women in Sapporo City, Japan
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Concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and dioxin-like polychlorinated biphenyls in blood collected from 195 pregnant women in Sapporo City, Japan

机译：日本札幌市195名孕妇血液中的多氯二苯并对二恶英，多氯二苯并呋喃和类二恶英类多氯联苯的浓度

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We measured the concentrations of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), non-ortho coplanar polychlorinated biphenyls (non-ortho PCBs), and mono-ortho coplanar polychlorinated biphenyls (mono-ortho PCBs) in blood collected between 2002 and 2004,from 195 pregnant women living in Sapporo City of Hokkaido Prefecture, Japan. The present study is one of the few studies in which PCDDs, PCDFs, and dioxin-like PCBs have been measured in the blood of pregnant women. Of the 195 pregnant women, 101 were primipara (mean: 28.8 years) and 94 were multipara (mean: 32.4 years). The arithmetic mean total TEQ concentrations of PCDDs, PCDFs, non-ortho PCBs, and mono-ortho PCBs of primiparous and multiparous mothers in Sapporo City were 17.4 (median: 15.7) and 14.0 (median: 13.9) pg TEQ/g lipid, respectively, and the concentrations were in the range of 6.6-43.4 and 3.4-28.2 pg TEQ/g lipid, respectively. In regard to the relationship between the total TEQ concentrations of PCDDs, PCDFs, non-ortho PCBs, and mono-ortho PCBs in maternal blood and the number of deliveries or age of primiparous and multiparius mothers, the levels of these dioxin-like compounds tended to decrease with increases in the number of deliveries and significantly increased with increasing maternal age in both groups. Furthermore, significant correlations were observed between the total TEQ concentrations of these dioxin like compounds and the age of primiparae and multiparae. The total TEQ concentration of PCDDs, PCDFs, non-ortho PCBs, and mono-ortho PCBs measured in 195 pregnant women has decreased compared to past levels in Japan for the last several decades. The results of the present study have indicated that dioxin contamination in the blood of young women in Japan is continuing to decrease.
机译：我们测量了血液中所收集的多氯二苯并对二恶英（PCDDs），多氯二苯并呋喃（PCDFs），非邻共平面多氯联苯（non-ortho PCBs）和单邻共平面多氯联苯（mono-ortho PCB）的浓度在2002年至2004年之间，居住在日本北海道札幌市的195名孕妇。本研究是为数不多的在孕妇血液中检测到PCDDs，PCDFs和二恶英样PCB的研究之一。在195名孕妇中，有101名是初产妇（平均年龄：28.8岁），有94名是多产妇（平均年龄：32.4岁）。札幌市初产和多产母亲的PCDDs，PCDFs，非原位PCB和单原位PCB的算术平均总TEQ浓度分别为pg TEQ / g脂质17.4（中位数：15.7）和14.0（中位数：13.9）pg TEQ / g脂质。的浓度分别在6.6-43.4和3.4-28.2 pg TEQ / g脂质之间。关于母体血液中PCDD，PCDF，非邻位多氯联苯和单邻位多氯联苯的总TEQ浓度与初产和多胎母亲的分娩次数或年龄之间的关系，这些二恶英样化合物的含量趋于增加两组的产妇数均随着分娩次数的增加而减少，并随着产妇年龄的增加而显着增加。此外，观察到这些二恶英样化合物的总TEQ浓度与primiparae和multiparae的年龄之间存在显着的相关性。与日本过去几十年来的水平相比，在195名孕妇中测得的PCDDs，PCDFs，非原位PCB和单原位PCB的总TEQ浓度有所下降。本研究的结果表明，日本年轻女性血液中的二恶英污染正在持续减少。

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