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首页> 外文期刊>The Chinese-German Journal of Clinical Oncology >Surgical Treatment of Carcinoma of Esophagus and Gastric Cardia―A 34-year Investigation
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Surgical Treatment of Carcinoma of Esophagus and Gastric Cardia―A 34-year Investigation

机译：食管癌和Card门癌的手术治疗-长达34年的研究

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Objective To understand the progress in surgical treatment of 12 970 patients with carcinoma of esophagus and gastric cardiac during 1965-1998. Methods The patients were divided into A, B and C groups: 3 155 patients (group A) were treated surgically in the first 14 years, 5 952 patients (group B) in the next 10 years, and 3 863 patients (group C) in the last 10 years. The early stage lesions (Tis, T1) were assigned as a separate group. The results of these groups were compared. Results The resectability for esophageal and gastric cardiac carcinoma was 94.0% and 84.4% respectively, and the overall resectability was 91.3% . The resectability for groups A, B, C and the early stage group was 82.1% , 85.1%, 90.2% and 100% , respectively. The overall operative mortality was 1.8%, it was 4.4% for group A, 1.6 % for group B, and 0.5% for group C. The overall 5-year survival was 31.6% . The 5-year survival for groups A, B, C and the early stage group was 27.0% , 29.1% , 32.0% and 92.6% , respectively. Among the 3 temporal groups, differences were observed in terms of lesion stage, location and size, surgery with or without combined therapy and postoperative complications. Conclusion Best results were achieved in the early cases, with a resectability of 100% and a 5-year survival of 92.6%. The indications for surgical treatment were extended with increased resectability and decreased mortality. Subtotal esophagectomy combined with cervical esophagogastrostomy was advocated as the procedure of first choice for esophageal carcinoma in attempt to diminish the chance of recurrence, and to achieve better outcomes by using combined therapy for patients with ≥ stage Ⅲ lesion.
机译：目的了解1965- 1998年12 970例食管癌和胃gastric门癌的手术治疗进展。方法将患者分为A，B和C组：头14年接受手术治疗的患者为3155名（A组），接下来10年接受了手术的患者为5952名（B组），C组为3863名患者（C组）在过去的十年中。早期病变（Tis，T1）被分为一个单独的组。比较了这些组的结果。结果食管和胃cardiac门癌的可切除性分别为94.0％和84.4％，总体可切除性为91.3％。 A，B，C组和早期组的可切除性分别为82.1％，85.1％，90.2％和100％。总体手术死亡率为1.8％，A组为4.4％，B组为1.6％，C组为0.5％。5年总生存率为31.6％。 A，B，C组和早期组的5年生存率分别为27.0％，29.1％，32.0％和92.6％。在3个颞骨组中，在病变阶段，位置和大小，有无联合治疗的手术以及术后并发症方面观察到差异。结论早期病例取得了最佳效果，可切除性为100％，5年生存率为92.6％。手术治疗的适应症随着可切除性的提高和死亡率的降低而扩大。食管癌次全切除联合颈段食管胃造口术被认为是食管癌的首选治疗方法，以期减少复发机会，并通过合并治疗治疗≥Ⅲ期病变的患者。

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