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首页> 外文期刊>Chinese Medical Journal >Retrospective investigation of hospitalized patients with atrial fibrillation in Mainland China
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Retrospective investigation of hospitalized patients with atrial fibrillation in Mainland China

机译：中国大陆住院房颤患者的回顾性调查

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Background Atrial fibrillation (AF) is a common arrhythmia associated with increased cardiovascular morbidity and mortality. This study was undertaken to analyze the epidemiological factors and evaluate the current status of treatment in patients with AF in Mainland China. Methods Retrospective analysis of hospital records were taken from patients with primary diagnosis of AF, discharged from January 1999 to December 2001. A total of 9297 cases (mean age 65.5 years) with AF were enrolled from 40 hospitals in major parts of China. Results The percentage of hospital admissions with AF was gradually increased comparing to those of total cardiovascular admission during three years, with the average of 7. 9%. The cases distribution progressively rose with age. The causes and associated conditions of AF: advanced age 58.1%, hypertension 40.3%, coronary heart disease 34.8%, heart failure 33.1%, rheumatic valvular disease 23.9% , idiopathic AF 7.4%, cardiomyopathy 5.4% , diabetes 4.1%. The most common coexistence among these variables was advanced age with hypertension. Permanent AF almost accounted for half of these cases (49.5%), paroxysmal and persistent AF were 33.7% and 16.7%, respectively. Paroxysmal AF was mainly treated with rhythm control (56.4%). However, 82.8% of patients with chronic AF had therapeutic strategy of rate control. In patients with persistent AF, the cardioversion had been attempted in cases more than 50%, with only 31.1% of these patients who could maintain stabilized sinus rhythm. The prevalence of stroke in this group was 17.5%. In nonvalvular AF patients the risk factors that significantly associated with stroke included advanced age, history of hypertension, coronary heart disease and type of AF. Sixty-four point five percent of these patients received antithrombotic therapy with dominated use of antiplatelet agents. The long-term prevention with anticoagulants only accounted for 6. 6%. In this investigation patients with antiplatelets as well as patients with anticoagulants showed significant lower stroke rate in comparison with those managed neither. However, the difference between antiplatelets and anticoagulants in terms of stroke rate was not significant. Conclusions Most epidemiological factors of AF from this group showed highly in accordance with those from the reports from other countries, such as age distribution, causes and associated conditions, type of AF, dominantly with approach of rate control. Both antiplatelet and anticoagulant treatments significantly reduced stroke rate. But there was no significant difference between these two kinds of treatments in reducing stroke rate.
机译：背景心房颤动（AF）是一种常见的心律不齐，与心血管疾病的发病率和死亡率增加有关。本研究旨在分析中国大陆房颤患者的流行病学因素并评估其治疗现状。方法回顾性分析1999年1月至2001年12月出院的初次诊断为AF的患者的病历。在中国主要地区的40所医院中，共纳入9297例AF患者（平均年龄65.5岁）。结果在三年内，AF患者的总住院率与总心血管疾病住院率相比逐渐增加，平均为7. 9％。随着年龄的增长，病例分布逐渐增加。房颤的病因和相关状况：高龄58.1％，高血压40.3％，冠心病34.8％，心力衰竭33.1％，风湿性瓣膜病23.9％，特发性房颤7.4％，心肌病5.4％，糖尿病4.1％。这些变量中最常见的共存是高血压。永久性AF几乎占这些病例的一半（49.5％），阵发性和持续性AF分别为33.7％和16.7％。阵发性房颤主要采用节律控制（56.4％）。然而，82.8％的慢性房颤患者具有控制心率的治疗策略。在持续性房颤患者中，尝试进行复律的患者超过50％，其中只有31.1％的患者可以维持稳定的窦性心律。该组中风的患病率为17.5％。在非瓣膜性房颤患者中，与中风显着相关的危险因素包括高龄，高血压病史，冠心病和房颤的类型。这些患者中有64％的患者接受了以抗血小板药物为主的抗血栓治疗。用抗凝剂长期预防仅占6. 6％。在这项研究中，抗血小板药物和抗凝药物的患者中风率均显着低于未接受抗血小板治疗的患者。但是，抗血小板药和抗凝剂之间的卒中率差异不明显。结论该组房颤的大多数流行病学因素均与其他国家的报告高度吻合，例如年龄分布，病因和相关状况，房颤的类型，主要是控制率。抗血小板和抗凝治疗均可显着降低卒中率。但是，这两种治疗方法在降低卒中率方面没有显着差异。

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