A possible mode of the specific recognition of nucleic acids by proteins

Li Xuqing; Liu Ciquan

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A possible mode of the specific recognition of nucleic acids by proteins

机译：蛋白质特异性识别核酸的一种可能模式

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Seven sets of protein target sites, which occur in several gene promoters, have been analyzed. The results suggest that there is a possible model of specific recognition of double - helical nucleic acids by proteins. This recognition mode is related to a special topological property of dou - ble - helical DNA, which is termed base spatial pattern (BSP) of DNA segment. BSP is the spatial topological property de - termined only by the spatial arrangement of the bases on double - helical DNA segment.

机译：分析了出现在几个基因启动子中的七组蛋白质靶位点。结果表明，存在蛋白质特异性识别双螺旋核酸的可能模型。这种识别方式与双螺旋DNA的特殊拓扑特性有关，这种特性称为DNA片段的基本空间模式（BSP）。 BSP是仅由双螺旋DNA片段上碱基的空间排列决定的空间拓扑特性。

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《Chinese science bulletin》 |2001年第11期|p.930-934|共5页
作者
Li Xuqing; Liu Ciquan;
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正文语种 eng
中图分类自然科学现状及发展;
关键词
protein; nucleic acids; recognition;

机译：蛋白;核酸;承认;

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专利

1. Editorial overview: Protein nucleic acid interactions: order, ambiguities and disorder in recognition and complex formation between proteins and nucleic acids [J] . Patel Dinshaw, Westhof Eric Current Opinion in Structural Biology . 2018,第期

机译：编辑概述：蛋白质核酸相互作用：识别和蛋白质和核酸之间的识别和复杂形成的顺序，歧义和紊乱
2. Covalent binding of modified nucleic acids to proteins as a method for investigation of specific protein - nucleic acid interactions [J] . T S Zatsepin, N G Dolinnaya, E A Kubareva, Russian Chemical Reviews: Reviews on Current Topics in Chemistry . 2005,第1期

机译：修饰核酸与蛋白质的共价结合作为研究特定蛋白质与核酸相互作用的方法
3. Nucleic Acid Sensors Involved in the Recognition of HBV in the Liver–Specific in vivo Transfection Mouse Models—Pattern Recognition Receptors and Sensors for HBV [J] . Chean Ring Leong, Hiroyuki Oshiumi, Misako Matsumoto, Medical Sciences . 2015,第2期

机译：核酸传感器参与肝脏特异性体内转染小鼠模型中HBV的识别— HBV的模式识别受体和传感器
4. High Pressure Gel Mobility Shift Analysis and Molecular Dynamics: Investigating Specific Protein-Nucleic Acid Recognition [C] . T.W. Lynch, M.A. McLean, D. Kosztin, International conference on high pressure bioscience and biotechnology . 2002

机译：高压凝胶迁移率移位分析和分子动力学：研究特定蛋白质 - 核酸识别
5. THE RESTRICTION ENDONUCLEASE ECO RI: ITS INTRINSIC METAL CENTER AND SPECIFIC INTERACTIONS WITH A DNA RECOGNITION SITE (PROTEIN-NUCLEIC ACID, ZINC METALLOENZYMES, INTERACTIONS CHIRAL METAL COMPLEXES, DNA-BINDING PROTEINS). [D] . PARANAWITHANA, SHANTHI R. 1986

机译：限制性内切酶Eco RI：其内在金属中心以及与DNA识别位点的特定相互作用（蛋白-核酸，锌金属酶，相互作用的手性金属络合物，DNA结合蛋白）。
6. Selective recognition of nucleic acids by proteins: the specificity of guanine interaction with carboxylate ions. [O] . G Lancelot, C Hélène 1977

机译：蛋白质对核酸的选择性识别：鸟嘌呤与羧酸根离子相互作用的特异性。
7. Selective recognition of nucleic acids by proteins: the specificity of guanine interaction with carboxylate ions. [O] . Lancelot, G, Hélène, C 1977

机译：蛋白质对核酸的选择性识别：鸟嘌呤与羧酸根离子相互作用的特异性。

A possible mode of the specific recognition of nucleic acids by proteins

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