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首页> 外文期刊>The Cleft Palate-Craniofacial Journal >Choanal Atresia and Rare Craniofacial Clefts: Report of Three Cases With a Review of the Literature
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Choanal Atresia and Rare Craniofacial Clefts: Report of Three Cases With a Review of the Literature

机译：胆道闭锁和罕见的颅面裂：三例报告并文献复习

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摘要

Objective: This retrospective study reports three cases associating choanal atresia (CA) and rare craniofacial clefts (RCFCs) described in Tessier's classification. Although still discussed, these two malformations could derive from the same embryopathogenic context, with an anomaly of migration of the neural crest cells as a common factor. In two of the three cases presented, the RCFC was diagnosed during the neonatal period, and the third case (case 3) was diagnosed at the age of 12 years. The knowledge of this malformative association must permit the diagnosis of CA as early as the neonatal period or through the thorough and directed examination of the children as part of the follow-up.
机译：目的：这项回顾性研究报告了3例与Tessier分类中描述的伴有闭锁性闭锁（CA）和罕见的颅面裂（RCFC）相关的病例。尽管仍在讨论中，但这两种畸形可能源自相同的胚胎致病性背景，其中神经c细胞迁移异常是一个共同因素。在所介绍的三例中，有两例在新生儿期被诊断为RCFC，第三例（病例3）在12岁时被诊断。了解这种畸形的联系必须允许在新生儿期早期或通过对孩子进行彻底和定向的检查作为诊断的一部分来诊断CA。

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