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Diagnosis of pancreatic tuberculosis by combined, contrast-enhanced sonography and endoscopic ultrasound-guided fine-needle aspiration

机译:超声造影和内镜超声引导下细针穿刺联合检查对胰腺结核的诊断

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摘要

A 79-year-old woman complaining of epigastric pain was examined by her local physician, who found an abdominal mass and referred the patient to our department. Abdominal plain computed tomography revealed a mass, 50 mm in size, with slight calcification on the ventral side of the head of the pancreas. On abdominal ultrasound, the mass lesion consisted of an aggregation of hypoechoic masses, with a heterogeneous hyperechoic region at its center. On contrast ultrasonography, only the hyperechoic region was stained. 18F-Fluorodeoxyglucose-positron emission tomography (FDG-PET) revealed FDG accumulation in the same region. It was difficult to differentiate between a malignant pancreatic tumor and an inflammatory disease on imaging, but since QuantiFERON TB2G testing was positive, pancreatic tuberculosis was suspected, and endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNA) was performed to obtain a definitive diagnosis. Samples from the hypoechoic region consisted of necrotic tissue, while those from the hyperechoic region consisted of pancreatic tissue together with granulation tissue. BCG immunostaining was positive, and a diagnosis of pancreatic tuberculosis was made. If EUS-FNA is performed on stained areas seen on contrast ultrasonography, this will probably enable a more accurate diagnosis of pancreatic tuberculosis with low invasiveness.
机译:当地医生对一名抱怨上腹部疼痛的79岁妇女进行了检查,该医生发现了腹部肿块,并将患者转诊至我科。腹部X线体层摄影术显示肿块大小为50 mm,胰头腹侧有轻度钙化。在腹部超声检查中,肿块病变由低回声肿块的聚集组成,中心处有异质性高回声区域。在对比超声检查中,仅高回声区域被染色。 18 F-氟去氧葡萄糖-正电子发射断层显像(FDG-PET)显示FDG在同一区域积聚。影像学上难以区分恶性胰腺肿瘤和炎性疾病,但由于QuantiFERON TB2G检测呈阳性,怀疑是胰腺结核,因此,进行了内镜超声引导下细针穿刺活检(EUS-FNA)以获得明确的诊断。低回声区域的样品由坏死组织组成,而高回声区域的样品则由胰腺组织和肉芽组织组成。 BCG免疫染色呈阳性,并诊断出胰腺结核。如果对对比超声检查所见的染色区域进行EUS-FNA,这可能会以较低的侵袭性更准确地诊断胰腺结核。

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