Automated Parallel Solid-Phase Synthesis of Non-Peptide CCR1 Receptor Antagonists

Brad O. Buckman Ameen Ghannam Angela Li Meina Liang Raju Mohan Howard P. Ng

首页> 外文期刊>Combinatorial Chemistry & High Throughput Screening >Automated Parallel Solid-Phase Synthesis of Non-Peptide CCR1 Receptor Antagonists

【24h】

Automated Parallel Solid-Phase Synthesis of Non-Peptide CCR1 Receptor Antagonists

机译：非肽CCR1受体拮抗剂的自动平行固相合成

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

An automated, parallel, solid-phase synthesis and screening strategy using commercially available aryl acetic acids as starting materials has discovered novel, non-peptide CCR1 antagonists (Ki < 100 nM).

机译：使用可商购的芳基乙酸作为起始原料的自动，平行，固相合成和筛选策略发现了新型的非肽CCR1拮抗剂（Ki <100 nM）。

著录项

来源
《Combinatorial Chemistry & High Throughput Screening》 |2002年第3期|p.249-251|共3页
作者
Brad O. Buckman Ameen Ghannam Angela Li Meina Liang Raju Mohan Howard P. Ng;
展开▼
作者单位

Berlex Biosciences, 15049San Pablo Ave, Richmond, CA 94804, USA;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类
关键词
solid-phase synthesis, ccri receptor antagonist;

机译：固相合成;ccri受体拮抗剂;

相似文献

外文文献
中文文献
专利

1. Automated parallel solid-phase synthesis of non-peptide CCR1 receptor antagonists. [J] . Buckman BO, Ghannam A, Angela L, Combinatorial chemistry & high throughput screening . 2002,第3期

机译：非肽CCR1受体拮抗剂的自动平行固相合成。
2. Discovery of Novel Non-Peptide CCR1 Receptor Antagonists [J] . David J. Triggle Chemtracts . 2000,第7期

机译：新型非肽CCR1受体拮抗剂的发现
3. Discovery of novel non-peptide CCR1 receptor antagonists. [J] . Ng HP, May K, Bauman JG, Journal of Medicinal Chemistry . 1999,第22期

机译：发现新型非肽CCR1受体拮抗剂。
4. Design,synthesis and modulation of angiogenesis by thrombin receptor non-peptide antagonists [C] . Kostas A.Alexopoulos, Michael Maragoudakis, John M.Matsoukas the International Peptide Symposium . 2001

机译：凝血酶受体非肽拮抗剂的设计，合成和调节血管生成
5. Peptide synthesis and characterization: Part 1. Synthesis and characterization of cyclic pseudopeptide analogs of endothelin antagonist BQ-123. Part 2. Comparative study of mild cleavage techniques for solid-phase synthesis of penta-, tetra-, and tri-peptides. [D] . Ingram, Darlene D. 2004

机译：肽的合成和表征：第1部分。内皮素拮抗剂BQ-123的环状假肽类似物的合成和表征。第2部分。五肽，四肽和三肽固相合成的轻度裂解技术的比较研究。
6. Design and Synthesis of Non-Peptide Mimetics Mapping the Immunodominant Myelin Basic Protein (MBP83–96) Epitope to Function as T-Cell Receptor Antagonists [O] . Mary-Patricia Yannakakis, Carmen Simal, Haralambos Tzoupis, 2017

机译：设计和合成拟肽的免疫肽髓鞘碱性蛋白（MBP83–96）表位以充当T细胞受体拮抗剂的非肽模拟物。
7. Design and synthesis of non-peptide mimetics mapping the immunodominant myelin basic protein (MBP83-96) epitope to function as T-Cell receptor antagonists [O] . Yannakakis Mary-Patricia, Simal Carmen, Tzoupis Haralambos, 2017

机译：设计和合成将免疫优势髓鞘碱性蛋白（MBP83-96）表位定位为T细胞受体拮抗剂的非肽模拟物
8. Structure Based, Solid-Phase Synthesis Approach to the Development of Novel Selective Estrogen Receptor Modulatory Steroids [R] . Hanson, R. N. 2002

机译：基于结构的固相合成方法开发新型选择性雌激素受体调节类固醇

Automated Parallel Solid-Phase Synthesis of Non-Peptide CCR1 Receptor Antagonists

摘要

著录项

相似文献

相关主题

期刊订阅