...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Computer Methods in Applied Mechanics and Engineering >A computational framework for fluid-solid-growth modeling in cardiovascular simulations
【24h】

A computational framework for fluid-solid-growth modeling in cardiovascular simulations

机译：心血管模拟中流体-固体-生长模型的计算框架

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

It is now well known that altered hemodynamics can alter the genes that are expressed by diverse vascular cells, which in turn plays a critical role in the ability of a blood vessel to adapt to new biomechanical conditions and governs the natural history of the progression of many types of disease. Fortunately, when taken together, recent advances in molecular and cell biology, in vivo medical imaging, biomechanics, computational mechanics, and computing power provide an unprecedented opportunity to begin to understand such hemodynamic effects on vascular biology, physiology, and pathophysiology. Moreover, with increased understanding will come the promise of improved designs for medical devices and clinical interventions. The goal of this paper, therefore, is to present a new computational framework that brings together recent advances in computational biosolid and biofluid mechanics that can exploit new information on the biology of vascular growth and remodeling as well as in vivo patient-specific medical imaging so as to enable realistic simulations of vascular adaptations, disease progression, and clinical intervention.
机译：众所周知，改变的血流动力学可以改变由各种血管细胞表达的基因，这反过来又在血管适应新的生物力学条件的能力中起着至关重要的作用，并控制着许多生物的自然发展史。疾病类型。幸运的是，综合起来看，分子和细胞生物学，体内医学成像，生物力学，计算力学和计算能力方面的最新进展为了解这种血液动力学对血管生物学，生理学和病理生理学的影响提供了前所未有的机会。此外，随着人们的了解越来越多，将有可能为医疗设备和临床干预措施改进设计。因此，本文的目的是提出一个新的计算框架，该框架汇集了生物固体和生物流体力学的最新进展，可以利用有关血管生长和重塑的生物学方面的新信息以及特定于患者的体内医学影像。以实现对血管适应，疾病进展和临床干预的现实模拟。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号