• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Current Immunology Reviews >Rallying the Troops: Innate Mucosal Responses to Enteric Pathogens
【24h】

Rallying the Troops: Innate Mucosal Responses to Enteric Pathogens

机译：集结部队：对肠病原体的固有粘膜反应

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The mucosal surfaces of the gastrointestinal tract are constantly exposed to large quantities of commensal microbes and enteric pathogens. Highly sophisticated innate immune mechanisms are in place to recognize and prevent the establishment of infections with such pathogens. At the same time, immune responses to commensals are being donwregulated resulting in a phenomen called oral tolerance. In turn, enteric pathogens have developed a variety of mechanisms to counter the immune response including novel colonization strategies and the production of virulence factors that can downregulate recognition and elimination by the innate immune system. This review focuses on enteric infections in large animals and describes the complex interplay between the host's innate immune system and pathogenic bacteria such as Escherichia coli, Salmonella spp., Campylobacter jejuni, Yersinia spp. and Shigella spp.
机译：胃肠道的粘膜表面不断暴露于大量的共生微生物和肠道病原体。建立了高度复杂的先天免疫机制，以识别和预防这种病原体的感染。同时，对礼拜的免疫反应被调节，导致一种叫做口服耐受的现象。反过来，肠道病原体已开发出多种抵抗免疫反应的机制，包括新颖的定殖策略和产生可下调先天免疫系统识别和清除的毒力因子。这篇综述着重于大型动物的肠道感染，并描述了宿主的先天免疫系统与致病菌（如大肠杆菌，沙门氏菌，空肠弯曲杆菌，耶尔森菌）之间的复杂相互作用。和志贺氏菌属。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号