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首页> 外文期刊>Current Organic Synthesis >Recent Advances of Bismuth(III) Salts in Organic Chemistry: Application to the Synthesis of Heterocycles of Pharmaceutical Interest
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Recent Advances of Bismuth(III) Salts in Organic Chemistry: Application to the Synthesis of Heterocycles of Pharmaceutical Interest

机译：铋（III）盐在有机化学中的最新进展：在合成具有药用价值的杂环化合物中的应用

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摘要

The use of bismuth(III) salts in organic synthesis has attracted an increasing interest over the last years. Systems comprising of bismuth(III) salts are generally catalytic and involve a relatively non-toxic metal. These features are of great interest in the area of green and pharmaceutical chemistry. Due to the fact a large number of natural compounds and known drugs are heterocycles, their construction and/or functionalization is of major interest. This review will focus on the uses of bismuth(III) salts in heterocyclic chemistry, as applied to the synthesis of compounds of pharmaceutical interest. In addition to the inclusion of five- and six-membered heterocycles, five- and six-membered heterocycles fused to one benzene ring, as well as other heterocyclic compounds, the application of bismuth(III) salts to chemistry of carbohydrates, nucleosides and β-lactams will also be considered.
机译：近年来，在有机合成中使用铋（III）盐引起了越来越多的兴趣。包含铋（III）盐的体系通常具有催化作用，并且涉及相对无毒的金属。这些功能在绿色和药物化学领域引起了极大的兴趣。由于大量的天然化合物和已知药物是杂环的事实，它们的构建和/或功能化是主要关注的问题。本文将重点介绍铋（III）盐在杂环化学中的用途，该化合物可用于合成具有药用价值的化合物。除了包含五元和六元杂环，与一个苯环稠合的五元和六元杂环以及其他杂环化合物外，铋（III）盐在碳水化合物，核苷和β的化学中的应用-内酰胺也将被考虑。

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