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Role of Glucocorticoids in Coat Depigmentation in Animals Selected for Behavior

机译：糖皮质激素在行为选择动物的外套色素沉着中的作用

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摘要

The involvement of glucocorticoid hormones in the appearance of white spots during embryogen-esis in domesticated gray rats was studied. It was shown that in fully pigmented gray rats, prenatal stress and exposure to dexamethasone on days 12-14 of gestation elicited a delay in the migration and development of melanoblasts in embryos. This led to a fourfold increase in the number of offspring with depigmentation on the ventral side of the body. It was also demonstrated that in adult offspring of mothers treated with dexam ethasone, the response of the hypothalamo-pituitary-adrenal axis to the emotional stress was lower compared to the controls. The role of glucocorticoids in the appearance of coat depigmentation under animal domes tication is discussed.
机译：研究了在家养的灰色大鼠胚胎发生期间糖皮质激素激素参与白斑出现的过程。研究表明，在全色素的灰色大鼠中，产前压力和妊娠第12-14天暴露于地塞米松会导致黑素母细胞在胚胎中的迁移和发育延迟。这导致后代身体腹侧色素沉着的后代数量增加了四倍。还证明了，在用地塞米松·ethasone治疗的母亲的成年后代中，下丘脑-垂体-肾上腺轴对情绪应激的反应比对照组低。讨论了在动物穹顶下糖皮质激素在外皮色素沉着外观中的作用。

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  • 来源
    《Cytology and genetics》 |2010年第5期|p.286-293|共8页
  • 作者

    I. N. Oskina; L. A. Prasolova; I. Z. Plyusnina; L. N. Trut;

  • 作者单位

    Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Novosibirsk, Russia;

    rnInstitute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Novosibirsk, Russia;

    rnInstitute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Novosibirsk, Russia;

    rnInstitute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Novosibirsk, Russia;

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