Gst Polymorphism And Cytogenetic Changes In Lung Tissues Of Lung Cancer Patients

N. N. Chakova; E. P. Mikhalenko; S. N. Polonetskaya; N. V. Chebotareva; Y. E. Demidchik; A. A. Zhilko; O. V. Kvitko; E. V. Krupnova

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Gst Polymorphism And Cytogenetic Changes In Lung Tissues Of Lung Cancer Patients

机译：肺癌患者肺组织Gst多态性与细胞遗传学变化

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Carriers of GSTT1 gene deletion were found to be more subject to a risk of emerging non-small-cell lung cancer (NSLC) than those of normal GSTT1 (+) genotype. A study of the relation between GST gene polymorphism and cytogenetic indices in lung cancer patients has shown a significant excess of the group average level in cells with micronuclei in NSLC patients with GSTTl(-). The frequency of cells with micronuclei was higher in smoking patients with a mutant genotype than in smoking carriers of the GSTT1 (+) genotype.

机译：发现GSTT1基因缺失的携带者比正常GSTT1（+）基因型的携带者更容易出现非小细胞肺癌（NSLC）。对肺癌患者中GST基因多态性与细胞遗传学指标之间关系的研究表明，GSTT1（-）的NSLC患者中微核细胞中的组平均水平显着过量。具有突变基因型的吸烟患者中具有微核细胞的频率高于具有GSTT1（+）基因型的吸烟携带者。

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《Cytology and genetics》 |2009年第1期|38-41|共4页
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N. N. Chakova; E. P. Mikhalenko; S. N. Polonetskaya; N. V. Chebotareva; Y. E. Demidchik; A. A. Zhilko; O. V. Kvitko; E. V. Krupnova;
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1. CYP and GST polymorphisms and survival in advanced non-small cell lung cancer patients. [J] . Ada AO, C Kunak S, Hancer F, Neoplasma: Journal of Experimental and Clinical Oncology . 2010,第6期

机译：CYP和GST多态性与晚期非小细胞肺癌患者的生存率。
2. CTLA-4 Expression and Polymorphisms in Lung Tissue of Patients with Diagnosed Non-Small-Cell Lung Cancer [J] . Adam Antczak, Dorota Pastuszak-Lewoska, Pawel Gdrski, BioMed research international . 2013,第Pta12期

机译：诊断为非小细胞肺癌的患者肺组织中的CTLA-4表达和多态性
3. CTLA-4 Expression and Polymorphisms in Lung Tissue of Patients with Diagnosed Non-Small-Cell Lung Cancer [J] . AdamAntczak, DorotaPastuszak-Lewandoska, Pawe?Górski, BioMed research international . 2013,第2期

机译：诊断为非小细胞肺癌的患者肺组织中的CTLA-4表达和多态性
4. The Lung Cancer Associated MicroRNAs and Single Nucleotides Polymorphisms: a Mendelian Randomization Analysis [C] . Ruixuan HUANG, William C. CHO, Yanni SUN, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2020

机译：肺癌相关的MicroRNA和单核苷酸多态性：孟德尔随机分析。
5. The Aging Lung and Cancer: Evidence of Field Cancerization from Transcriptional Profiles of Normal Human and Mouse Lung Tissues. [D] . Villeneuve, Patrick James. 2010

机译：衰老的肺癌和癌症：从正常人和小鼠肺组织的转录谱中发现田野癌化的证据。
6. Association of GSTs gene polymorphisms with treatment outcome of advanced non-small cell lung cancer patients with cisplatin-based chemotherapy [O] . Gun Wu, Bin Jiang, Xiaoqin Liu, 2015

机译：GSTs基因多态性与晚期非小细胞肺癌顺铂化疗的疗效相关性
7. P2-140: GSTT1 polymorphism and cytogenetic changes in peripheral blood and tissues of patients suffering from lung cancer [O] . Mikhalenka Alena, Chakava Natalia, Palanetskaya Swetlana, 2007

机译：P2-140：肺癌患者外周血和组织中GSTT1多态性和细胞遗传学变化

Gst Polymorphism And Cytogenetic Changes In Lung Tissues Of Lung Cancer Patients

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