...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Cytology and genetics >Molecular and Structural-Biological Analysis of Nicotiana plumbaginifolia Mutants for Identification of the Site on Their β-Tubulins of Interaction with Dinitroanilines and Phosphorothioamides
【24h】

Molecular and Structural-Biological Analysis of Nicotiana plumbaginifolia Mutants for Identification of the Site on Their β-Tubulins of Interaction with Dinitroanilines and Phosphorothioamides

机译：烟草李子突变体的分子和结构生物学分析，用于鉴定其β-微管蛋白与二硝基苯胺和硫代磷酰胺相互作用的位点

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The identification of the location of a point mutation on β-tubulin molecules of amiprophosmethyl-and trifluralin-resistant Nicotiana plumbaginifolia lines are described in this work. It was shown that in the first case, this mutation is related with the substitution of serine residue for proline in position 248; in the second case, with the substitution of phenylalanine for serine in position 317 of the β-tubulin's amino acid sequence. Three-dimensional models of the β-tubulin molecule from Chlamydomonas with the well-known location of mutations determining dinitroaniline- and phosphorothioamides resistance (the substitution of lysine residue for methionine in position 350), and β-tubulin from Nicotiana plumbagnifolia have been reconstructed. On the basis of the analysis of the interaction site for dinitroanilines and phosphorothioamides located on the Chlamydomonas β-tubulin's molecule it was concluded that the revealed mutations on Nicotiana plumbaginifolia β-tubulin are affected by the residues of the amino acids, participating in the formation of this site.
机译：在这项工作中描述了对虫甲基和三氟拉林抗性的Nicotiana plumbaginifolia系的β-微管蛋白分子上点突变位置的鉴定。结果表明，在第一种情况下，该突变与位置248上脯氨酸的丝氨酸残基取代有关；在第二种情况下，用β-微管蛋白氨基酸序列第317位的苯丙氨酸代替丝氨酸。已经重建了衣藻的β-微管蛋白分子的三维模型，该模型具有确定二硝基苯胺和硫代磷酰胺抗性的突变的众所周知的位置（赖氨酸残基取代蛋氨酸在位置350），以及烟草（Nicotiana plumbagnifolia）的β-微管蛋白已被重建。在分析衣藻β-微管蛋白分子上的二硝基苯胺和硫代磷酸酰胺的相互作用位点的基础上，得出的结论是，烟草中发现的突变受到氨基酸残基的影响，参与了β-微管蛋白的形成。这个网站。

著录项

  • 来源
    《Cytology and genetics》 |2009年第5期|352-359|共8页
  • 作者

    A. I. Yemets; W. V. Baird; A. Yu. Nyporko; G. A. Swire-Clark; Ya. B. Blume;

  • 作者单位

    Institute of Food Biotechnology and Genomics, National Academy of Sciences of Ukraine, Kiev, Ukraine;

    Clemson University, E-143 P&AS Bldg., Clemson, South Carolina, 29634 USA;

    Institute of Food Biotechnology and Genomics, National Academy of Sciences of Ukraine, Kiev, Ukraine;

    Clemson University, E-143 P&AS Bldg., Clemson, South Carolina, 29634 USA;

    Institute of Food Biotechnology and Genomics, National Academy of Sciences of Ukraine, Kiev, Ukraine;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号