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Electroencephalogram abnormalities in panic disorder patients: a study of symptom characteristics and pathology

机译：恐慌症患者的脑电图异常：症状特征和病理学研究

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Background Since the 1980s, a high EEG abnormality rate has been reported for patients with panic disorder. However, how the EEG abnormalities of panic disorder patients are related to the clinical features and pathology of these patients has yet to be clarified. In this study we investigated whether or not EEG abnormalities are related to the 13 symptoms in the DSM-IV criteria for a diagnosis of panic attacks. Methods Subjects were 70 patients diagnosed with panic disorder. Logistic regression analysis was performed with EEG findings as dependent variables and age, sex and with or without the 13 symptoms as independent variables. Results (1)EEG findings for panic disorder patients with EEG abnormalities: Of the 17 patients, 13 had repeated slow waves in the θ-band; the most prevalent EEG abnormality found in this study. Paroxysmal abnormality interpreted as epileptiform was found in only two cases. (2)Nausea or abdominal distress (37.7% vs 82.45%, OR-12.5), derealization or depersonalization (7.5% vs 47.1%, OR = 13.9,) and paresthesias (43.4% vs 64.7%, OR = 7.9,) were extracted by multivariate analysis as factors related to EEG abnormalities. Conclusion Of the 70 patients studied, 17 had EEG abnormalities. Among these 17 cases, "repeated slow waves in the θ-band" was the most common abnormality. The factors identified as being related to EEG abnormalities are nausea or abdominal distress, derealization or depersonalization, and paresthesias. The study indicated that physiological predispositions are closely related to panic attacks.
机译：背景技术自1980年代以来，已报道恐慌症患者的脑电图异常率很高。然而，恐慌症患者的脑电图异常如何与这些患者的临床特征和病理学相关尚待阐明。在这项研究中，我们调查了脑电图异常是否与DSM-IV诊断惊恐发作标准中的13种症状有关。方法研究对象为70名被诊断为惊恐症的患者。进行逻辑回归分析，将脑电图结果作为因变量，以年龄，性别和有无13种症状为自变量。结果（1）脑电图异常的惊恐障碍患者的脑电图结果：17例患者中，有13例在θ波段反复出现慢波;在17例患者中，有13例出现重复的慢波。在这项研究中发现的最普遍的脑电图异常。仅两例发现阵发性异常，被解释为癫痫样。 （2）提取出恶心或腹部不适（37.7％vs 82.45％，OR-12.5），虚幻或去个性化（7.5％vs 47.1％，OR = 13.9）和感觉异常（43.4％vs 64.7％，OR = 7.9）通过多元分析作为与脑电图异常相关的因素。结论在研究的70例患者中，有17例脑电图异常。在这17例病例中，“重复的θ波段慢波”是最常见的异常。被确定与脑电图异常相关的因素是恶心或腹部不适，虚脱或人格失调以及感觉异常。研究表明，生理易感性与惊恐发作密切相关。

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