• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>BioPsychoSocial Medicine >Helplessness and perceived pain intensity: relations to cortisol concentrations after electrocutaneous stimulation in healthy young men
【24h】

Helplessness and perceived pain intensity: relations to cortisol concentrations after electrocutaneous stimulation in healthy young men

机译：无助和感觉到的疼痛强度：健康年轻人中经皮电刺激后皮质醇浓度的关系

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background Uncontrollable aversive events are associated with feelings of helplessness and cortisol elevation and are suitable as a model of depression. The high comorbidity of depression and pain symptoms and the importance of controllability in both conditions are clinically well-known but empirical studies are scarce. The study investigated the relationship of pain experience, helplessness, and cortisol secretion after controllable vs. uncontrollable electric skin stimulation in healthy male individuals. Methods Sixty-four male volunteers were randomly assigned to receive 30 controllable (self-administered) or uncontrollable (experimenter-administered) painful electric skin stimuli. Perceived pain intensity (PPI), subjective helplessness ratings, and salivary cortisol concentrations were assessed. PPI was assessed after stress exposure. For salivary cortisol concentrations and subjective helplessness ratings, areas under the response curve (AUC) were calculated. Results After uncontrollable vs. controllable stress exposure significantly higher PPI ratings (P = 0.023), higher subjective helplessness AUC (P Conclusions The results confirm the impact of uncontrollability on stress responses in humans; the relationship of PPI with subjective helplessness and salivary cortisol suggests a cognitive-affective sensitization of pain perception, particularly under uncontrollable conditions.
机译：背景不可控制的厌恶事件与无助感和皮质醇升高相关，适合作为抑郁症的模型。抑郁和疼痛症状的高合并症以及两种情况下可控性的重要性在临床上都是众所周知的，但缺乏实证研究。该研究调查了健康男性个体中可控与不可控电刺激皮肤后疼痛经历，无助感和皮质醇分泌之间的关系。方法随机分配64名男性志愿者接受30种可控（自我管理）或不可控制（实验者管理）的疼痛性皮肤电刺激。评估知觉疼痛强度（PPI），主观无助等级和唾液皮质醇浓度。压力暴露后评估PPI。对于唾液皮质醇浓度和主观无助等级，计算了反应曲线下的面积（AUC）。结果不可控制与可控制的压力暴露后，PPI评分显着较高（P = 0.023），主观无助性AUC较高（P结论）结果证实了不可控制性对人的应激反应的影响; PPI与主观无助和唾液皮质醇的关系表明：疼痛感知的认知情感敏化，尤其是在无法控制的条件下。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号