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The Epidemiology of Guillain-Barré Syndrome in Children under 15 Years Old in Southwest Iran

机译：伊朗西南部15岁以下儿童吉兰-巴雷综合征的流行病学

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Background: Guillain-Barré syndrome (GBS) is an acute inflammatory polyneuropathy, which has become the most common cause of acute flaccid paralysis. An accurate estimation of GBS occurrence would be useful for investigating the potential causal relationships between risk factors and GBS. The aim of the study was to analyze the incidence, annual time trend, and some epidemiological aspects of GBS in children in the Southwest of Iran. Methods: This was a retrospective study conducted by the Department of Pediatrics of Ahvaz Jundishapur University of Medical Sciences from January 2006 to December 2015. We extracted data from the national database of Acute Flaccid Paralysis Surveillance System. Results: A total of 184 subjects with GBS were assessed. The mean age of subjects was 5.43 ± 4.07 years. The average annual incidence rate of GBS was 1.51 per 100,000 children under 15 years old (95% CI: 1.29-1.73). There was no significant statistical difference in GBS incidence rate between girls and boys ( p = 0.376). The highest and lowest proportions of the GBS occurrences were in autumn (32.2%) and summer (14.7%), respectively. Conclusions: The findings indicated that the annual incidence rate of GBS in this study was similar to those in other studies in this area.
机译：背景：格林-巴利综合征（GBS）是一种急性炎症性多发性神经病，已成为急性弛缓性麻痹的最常见原因。准确估算GBS发生率将有助于调查风险因素与GBS之间的潜在因果关系。这项研究的目的是分析伊朗西南部儿童中GBS的发生率，年际趋势和一些流行病学方面。方法：这是一项由阿瓦兹·jundishapur医科大学儿科于2006年1月至2015年12月进行的回顾性研究。我们从急性弛缓性麻痹监测系统的国家数据库中提取了数据。结果：共评估了184名GBS受试者。受试者的平均年龄为5.43±4.07岁。 GBS的平均年发病率为每10万名15岁以下的儿童1.51（95％CI：1.29-1.73）。男女之间的GBS发生率无统计学差异（p = 0.376）。 GBS发生率的最高和最低比例分别是秋季（32.2％）和夏季（14.7％）。结论：研究结果表明，GBS的年发病率与该领域的其他研究相似。

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