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Green odor attenuates a cold pressor test-induced cardiovascular response in healthy adults

机译:绿色气味减弱健康成年人因冷压试验引起的心血管反应

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Background Green odor, a mixture of equal amounts of 2E-hexenal (leaf aldehyde) and 3Z-hexenol (leaf alcohol) has been demonstrated to have an anti-stress effect in rats. This study investigated whether or not green odor also has an anti-stress effect in humans. Methods Changes in blood pressure, heart rate, and the skin temperature of a fingertip were observed after presenting green odor at a concentration of 0.03% or vehicle via inhalation through the nose for 10 min to eight healthy normotensive adults. We also assessed the pleasantness of green odor and its effect on mood states via assessment with the Profile of Mood States (POMS) questionnaire. Cardiovascular response to green odor and the vehicle were compared among 11 additional healthy adults by use of the cold pressor test. Results Of 19 subjects, 15 (79%) reported that the green odor was pleasant. Green odor had no effect on blood pressure, heart rate, skin temperature, or POMS score under non-stressful conditions. In the second experiment, green odor attenuated cold pressor test-induced increases in systolic and diastolic blood pressure and facilitated the recovery of skin temperature. Conclusion These findings suggest that green odor has an anti-stress effect in healthy humans.
机译:背景技术绿色气味,等量的2E-己醛(叶醛)和3Z-己烯醇(叶醇)的混合物已证明对大鼠具有抗应激作用。这项研究调查了绿色气味是否也对人体具有抗应激作用。方法对八名健康的正常血压成年人,经鼻吸入10分钟后,出现浓度为0.03%的绿色气味或赋形剂后,观察血压,心率和指尖皮肤温度的变化。我们还通过情绪状态概况(POMS)问卷进行评估,评估了绿色气味的愉悦性及其对情绪状态的影响。通过使用冷压试验,在另外11名健康成年人中比较了对绿色气味和媒介物的心血管反应。结果在19名受试者中,有15名(79%)报告绿色气味令人愉快。在非压力条件下,绿色气味对血压,心率,皮肤温度或POMS评分没有影响。在第二个实验中,绿色气味减弱了冷压试验引起的收缩压和舒张压的升高,并促进了皮肤温度的恢复。结论这些发现表明,绿色气味对健康人具有抗应激作用。

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