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首页> 外文期刊>BioTechnology: An Indian Journal >Effect of bael bark extracts againstEscherichia coli -Afood borne pathogen
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Effect of bael bark extracts againstEscherichia coli -Afood borne pathogen

机译：鲍尔皮提取物对大肠杆菌的影响-食源性病原体

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Food borne illness has developed serious threat to children and elderly people and the causative organism is gaining resistance over usage of synthetic formulations and drugs. The usage of medicinal plants could cover up the health aspects and offer newer source of antibacterial, antifungal agents which can be effective against pathogenic organism. The increase in resistant of pathogenic food borne illness causing organism has to be declined by developing newer type of drug which is consists of significant effect over it. The Aegle marmelos [bael] of family Rutaceae is considered as sacred tree among Indians and possess good medicinal properties. The food borne pathogen Escherichia coli were tested against bark extracts of Aegle marmelos by standard well diffusion method at varying concentration from50mg/ml-250mg/ml. The extractswere prepared by standard procedure of 1:5 ratio of bark and solvent in soxhlet apparatus. The test resultswere compared with commercial antibiotic ampicillin. The sensitive of E.coli against hexane extract of bael bark is 30mm at concentration of 250mg/ml and 24mmof inhibition zone for aqueous extract of bael bark. The commercial antibiotic sensitive against test species is recorded about to be 30mmat 250mg/ml concentration. The bark extracts against E.coli were showing sensitive inhibition zones as that of the commercial antibiotic which is ofmaximumat 250mg/ml concentration and it could easily lead to the development of newer synthetic, chemical and pharmaceutical compound for the treatment or control of food borne illness which is making serious impact on both developing and developed countries. Effective studies against the definite active biological compound could be significantly studied to develop further more chemical compounds for treating other pathogens.
机译：食源性疾病已严重威胁儿童和老年人，并且致病性有机体对合成制剂和药物的使用产生了抵抗力。药用植物的使用可以掩盖健康方面的问题，并提供可有效对抗病原生物的抗菌，抗真菌剂的新来源。致病性食源性疾病引起的生物体的抗药性增加必须通过开发新型药物来降低，这种药物具有明显的作用。芸香科的淡黄色神ba [bael]被认为是印第安人中的神圣树，并具有良好的药用特性。通过标准的孔扩散方法，以50mg / ml-250mg / ml的不同浓度，对食源性病原体大肠杆菌进行了抗马格勒树皮提取物测试。在索氏提取器中按1∶5的树皮和溶剂比例的标准程序制备提取物。将测试结果与市售抗生素氨苄西林进行比较。大肠杆菌对ba树皮己烷提取物的敏感性为30mm，浓度为250mg / ml，对ba树皮水提取物的抑制区为24mm。记录的对测试物种敏感的商业抗生素浓度约为250mg / ml，浓度为30mm。与大肠杆菌相比，树皮提取物显示出对抗生素的敏感抑制区，最大浓度为250mg / ml，很容易导致开发用于治疗或控制食源性疾病的新型合成，化学和药物化合物这对发展中国家和发达国家都产生了严重影响。可以对针对这种确定的活性生物化合物的有效研究进行重大研究，以开发更多的化学化合物来治疗其他病原体。

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