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首页> 外文期刊>BMC Ophthalmology >Prevalence and risk factors of primary open-angle glaucoma in a city of Eastern China: a population-based study in Pudong New District, Shanghai
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Prevalence and risk factors of primary open-angle glaucoma in a city of Eastern China: a population-based study in Pudong New District, Shanghai

机译：东部城市原发性开角型青光眼的患病率和危险因素：基于人口的上海浦东新区研究

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Background The aim of the present study was to investigate the prevalence and characteristics of primary open-angle glaucoma among the urban population of Pudong New District, Shanghai. Methods Three residents’ committees were randomly selected from Pudong New District, and residents aged 50 and older were screened for primary open-angle glaucoma (POAG) from March to April 2011. In remote screening, the tests on visual acuity, refraction, intraocular pressure (IOP), and the photographs of anterior segment and fundus were used to identify POAG suspect. The suspected subjects were then reexamined with the tests on IOP, gonioscopy, Humphrey visual field test, and retinal nerve fiber layer (RNFL) thickness by optical coherence tomography (OCT). POAG was diagnosed according to the criteria defined by International Society for Geographic and Epidemiological Ophthalmology (ISGEO). Finally, POAG risk factors were evaluated using logistic regression analysis. Results A total of 2528 citizens out of 3,146 eligible residents (80.36?%) participated in this study. Among the citizens, 72 were diagnosed to have POAG, giving the crude prevalence rate of 2.85?% (95?% CI:2.20?%–3.50?%) in general and age- and gender-adjusted prevalence rate of 2.8?% (95?% CI: 2.78?%–2.83?%). Among the 72 POAG patients, only 22 cases had IOP exceeding 21?mmHg while other 50 cases had IOP of 21?mmHg or less; nine cases had one eye blind (12.5?%). Intriguingly, only eight cases (11.11?%) had been diagnosed with POAG before this screening. Conclusions More efforts are required for early screening and education on POAG in communities, especially in a POAG high-risk population.
机译：背景技术本研究的目的是调查上海市浦东新区城市人群原发性开角型青光眼的患病率和特征。方法于2011年3月至2011年4月，从浦东新区随机抽取三个居民委员会，对50岁及以上的居民进行原发性开角型青光眼（POAG）筛查。在远程筛查中，进行视力，屈光度，眼压测试（IOP），并使用前段和眼底的照片来识别POAG嫌疑犯。然后通过光学相干断层扫描（OCT）对可疑对象进行IOP，角膜镜检查，汉弗莱视野测试和视网膜神经纤维层（RNFL）厚度测试。根据国际地理和流行病眼科协会（ISGEO）定义的标准诊断POAG。最后，使用逻辑回归分析评估了POAG危险因素。结果3146名符合条件的居民中，共有2528名公民（占80.36％）参加了这项研究。在所有公民中，有72名被诊断患有POAG，粗略患病率为2.85％（95％CI：2.20％-3.50％），而按年龄和性别调整的患病率为2.8％（ 95％CI：2.78％–2.83％）。在72例POAG患者中，只有22例眼压超过21？mmHg，而其他50例眼压为21？mmHg或更低。 9例有1只眼盲（12.5％）。有趣的是，在此筛查之前仅诊断出8例（11.11％）POAG。结论在社区，尤其是在POAG高危人群中，对POAG进行早期筛查和教育需要付出更多的努力。

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