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Visual Aids for Multimodal Treatment Options to Support Decision Making of Patients with Colorectal Cancer

机译:多模态治疗方案的视觉辅助,可支持大肠癌患者的决策

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Background A variety of multimodal treatment options are available for colorectal cancer and many patients want to be involved in decisions about their therapies. However, their desire for autonomy is limited by lack of disease-specific knowledge. Visual aids may be helpful tools to present complex data in an easy-to-understand, graphic form to lay persons. The aim of the present study was to evaluate the treatment preferences of healthy persons and patients using visual aids depicting multimodal treatment options for colorectal cancer. Methods We designed visual aids for treatment scenarios based on four key studies concerning multimodal treatment of colorectal cancer. The visual aids were composed of diagrams depicting outcome parameters and side effects of two treatment options. They were presented to healthy persons (n?=?265) and to patients with colorectal cancer (n?=?102). Results Most patients and healthy persons could make immediate decisions after seeing the diagrams (range: 88% – 100%). Patients (79%) chose the intensive-treatment option in the scenario with a clear survival benefit. In scenarios without survival benefit, all groups clearly preferred the milder treatment option (range: 78% - 90%). No preference was seen in the scenario depicting equally intense treatment options with different timing (neoadjuvant vs. adjuvant) but without survival benefit. Conclusions Healthy persons’ and patients’ decisions using visual aids seem to be influenced by quality-of-life aspects rather than recurrence rates especially in situations without survival benefit. In the future visual aids may help to improve the management of patients with colorectal cancer.
机译:背景技术结直肠癌有多种多样的治疗选择,许多患者希望参与其治疗的决策。但是,由于缺乏疾病特定的知识,他们对自治的渴望受到了限制。视觉辅助工具可能是有用的工具,可以以易于理解的图形形式向躺着的人展示复杂的数据。本研究的目的是使用视觉辅助工具评估健康人和患者的治疗偏好,该辅助工具描述了结直肠癌的多模式治疗方案。方法我们基于涉及大肠癌多式联运治疗的四项关键研究设计了用于治疗方案的视觉辅助工具。视觉辅助工具由描述两种治疗方案的结果参数和副作用的图表组成。他们被呈现给健康人(n = 265)和大肠癌患者(n = 102)。结果大多数患者和健康人都可以在查看图表后立即做出决定(范围:88%– 100%)。在这种情况下,患者(79%)选择了强化治疗方案,具有明显的生存获益。在没有生存利益的情况下,所有组显然都希望选择较温和的治疗方案(范围:78%-90%)。在描述了同样激烈的治疗方案,不同的时机(新辅助剂与辅助剂)但没有生存获益的方案中,没有发现偏好。结论健康人和患者使用视力辅助器的决定似乎受生活质量方面的影响,而不是复发率的影响,尤其是在没有生存利益的情况下。将来,视觉辅助工具可能有助于改善大肠癌患者的治疗。

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