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首页> 外文期刊>BMC Ophthalmology >The observation during small incision lenticule extraction for myopia with corneal opacity
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The observation during small incision lenticule extraction for myopia with corneal opacity

机译：小切口小孔摘除角膜混浊近视的观察

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Background To evaluate the feasibility and efficacy of small incision lenticule extraction (SMILE) in the treatment of myopia with corneal opacity. Methods To evaluate the treatment of myopia with corneal opacity, 9 patients (4 males, 5 females) who underwent SMILE were enrolled in this prospective clinical study. One eye of each patient was treated. The results of laser scanning and lenticule extraction were observed during the surgery, and the surgical videos were again reviewed after surgery. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), and spherical equivalence (SE) were noted at 1?month after surgery. The depth and density of the corneal opacities were measured by anterior segment optical coherence tomography (AS-OCT) and the Pentacam anterior eye segment analyzer. Results All procedures were uneventful and no intraoperative complications were observed. At 1?month after surgery, the UDVA of all patients was 20/25 or better and no patients lost Snellen lines. The mean safety and efficacy indexes were 1.10?±?0.24 and 1.08?±?0.16, respectively, at 1?month postoperatively. The mean postoperative spherical equivalent was 0.27?±?0.23 diopter (D). All eyes were within ±0.75 D and 8 eyes (88.9%) were within ±0.50 D. There was no eccentric corneal topography or abnormal morphology in the corneal caps. The corneal opacities of all patients were within the optical zone. The mean preoperative depths in the deepest areas of corneal opacity were 152?±?38?μm (range: 86–217?μm); at 1?month after surgery ( P ?.05), it was 49.8?±?26.7 (range: 19.8 to 82.5) at 1?month after surgery. Conclusion Patients with corneal opacity can be successfully treated with the SMILE operation. The short-term outcome was good, however the long-term results need further study. Trial registration The trial registration number: ChiCTR-ONRC-13003114 , Date of Last Refreshed on: 2016-01-27, Date of registration on 2013-03-17(retrospectively registered).
机译：背景技术评价小切口小孔镜提取术（SMILE）治疗角膜混浊近视的可行性和有效性。方法为评估近视合并角膜混浊的治疗效果，本研究纳入了9例接受SMILE治疗的患者（男4例，女5例）。每位患者一只眼睛被治疗。在手术过程中观察到激光扫描和微透镜提取的结果，并在手术后再次回顾手术录像。术后1个月发现未矫正远视力（UDVA），矫正远视力（CDVA）和球当量（SE）。角膜混浊的深度和密度通过前节光学相干断层扫描（AS-OCT）和Pentacam前眼节分析仪进行测量。结果所有手术均顺利进行，无术中并发症发生。术后1个月，所有患者的UDVA为20/25或更高，没有患者失去Snellen谱系。术后1个月的平均安全性和有效性指数分别为1.10±0.24和1.08±0.16。术后平均球当量为0.27±0.23屈光度（D）。所有眼睛均在±0.75 D之内，8眼（88.9％）在±0.50 D之内。角膜帽无偏心角膜地形图或异常形态。所有患者的角膜混浊均在视区内。角膜混浊最深区域的术前平均深度为152？±？38？μm（范围：86–217？μm）;术后1个月时（P <0.05），在术后1个月时为49.8±26.7（范围：19.8至82.5）。结论SMILE手术可以成功治疗角膜混浊。短期结果是好的，但是长期结果有待进一步研究。试用注册试用注册号：ChiCTR-ONRC-13003114，最后更新日期：2016-01-27，注册日期2013-03-17（已追溯注册）。

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