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A case of pseudoxanthoma elasticum with proliferative diabetic retinopathy

机译:弹性假黄瘤伴增生性糖尿病视网膜病变1例

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Background To report the case of a patient with pseudoxanthoma elasticum (PXE) and proliferative diabetic retinopathy (PDR), and discuss the relationship between PXE and diabetic retinopathy (DR). Case presentation A 47-year-old man with PXE presented with angioid streaks and DR in both eyes, and bilateral panretinal photocoagulation was performed for treatment. Vitrectomy had previously been performed in his right eye for vitreous hemorrhage due to PDR. Systemic findings included multiple, discrete, symmetrical, small yellow papules bilaterally in the axilla and inguinal region. Examination on presentation showed vitreous hemorrhage in his left eye, and vitrectomy was performed for treatment. Intraoperative findings showed fibrovascular membrane around the optic disc and vascular arcade. A mottled fundus (peau d’orange appearance) associated with angioid streaks was also present, yet there was no evident choroidal neovascularization (CNV). The postoperative course was satisfactory, and corrected visual acuity improved from 0.02 to 0.7 diopters. Conclusion Despite the peau d’orange appearance in both eyes of this case, no CNV was evident. The vitreous hemorrhage was thus attributed to PDR. Moreover, we reviewed the published literature and discuss the relationship between PXE and DR.
机译:背景技术报道弹性假性黄瘤(PXE)和增生性糖尿病视网膜病变(PDR)患者的病例,并讨论PXE与糖尿病性视网膜病变(DR)之间的关系。病例介绍一名47岁的PXE男性双眼出现血管样条纹和DR,并进行了双侧全视网膜光凝治疗。先前曾在右眼进行过玻璃体切除术,以治疗因PDR引起的玻璃体出血。系统性发现包括腋窝和腹股沟区双侧多个,离散,对称的小黄色丘疹。体格检查显示左眼有玻璃体出血,并进行了玻璃体切除术进行治疗。术中发现在视盘和血管拱门周围有纤维血管膜。还出现了与血管样条纹相关的斑驳的眼底(外观为橙色),但没有明显的脉络膜新生血管形成(CNV)。术后过程令人满意,矫正视力从0.02屈光度提高到0.7屈光度。结论尽管在本例中两只眼睛都呈棕褐色,但没有发现CNV。玻璃体出血因此归因于PDR。此外,我们回顾了已发表的文献并讨论了PXE和DR之间的关系。

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