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首页> 外文期刊>BMC Urology >Comparison of continence outcomes of early catheter removal on postoperative day 2 and 4 after laparoscopic radical prostatectomy: a randomized controlled trial
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Comparison of continence outcomes of early catheter removal on postoperative day 2 and 4 after laparoscopic radical prostatectomy: a randomized controlled trial

机译：腹腔镜前列腺癌根治术后术后第2天和第4天早期拔除导管的尿失禁结果比较：一项随机对照试验

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Background The optimal timing of catheter removal following laparoscopic radical prostatectomy (LRP) has not yet been determined. This prospective study was designed to compare the efficacy and safety of catheter removal on postoperative day (POD) 2 versus POD 4 after LRP and its impact on urinary continence outcomes. Methods One hundred and thirteen patients underwent LRP and were prospectively randomized into two groups: group 1 (n?=?57) had the urinary catheter removed on POD 2 while group 2 (n?=?56) had the catheter removed on POD 4. The urine loss ratio (ULR) was defined as the weight of urine loss in the pad divided by the daily micturition volume. Continence was defined as a pad-free status. Results No significant differences were observed in clinical features between groups 1 and 2. Acute urinary retention (AUR) after catheter removal occurred in 21 patients (18.6?%) (13 (22.8?%) in group 1 and 8 (14.3?%) in group 2 (p?=?0.244). The first-day mean ULR values were 1.16?±?4.95 in group 1 and 1.02?±?3.27 in group 2 (p?=?0.870). The last-day mean ULR values were 0.57?±?1.60 in group 1 and 2.78?±?15.49 in group 2 (p?=?0.353). Continence rates at 3, 6, 9, and 12?months were 21.8, 41.1, 58.0, and 71.4?% in group 1 and 34.5, 66.0, 79.2, and 83.7?% in group 2 (p?=?0.138, 0.009, 0.024, and 0.146, respectively). In AUR cases, continence rates at 3, 6, 9, and 12?months were 0, 23.1, 38.5, and 54.5?% in group 1 and 37.5, 75.0, 87.5, and 87.5?% in group 2 (p?=?0.017, 0.020, 0.027, and 0.127, respectively). A multivariate analysis identified AUR after catheter removal on POD 2 as the only predictive factor for incontinence 6 and 9?months after LRP (p?=?0.030 and 0.018, respectively). Conclusions Our results demonstrated that early catheter removal on POD 2 after LRP may increase the risk of incontinence. Trial registration The study was registered as Clinical trial: ( UMIN000014944 ); registration date: 12 March 2012.
机译：背景技术腹腔镜根治性前列腺切除术（LRP）后导管移除的最佳时机尚未确定。这项前瞻性研究旨在比较LRP术后术后第2天（POD）与第4天POD的有效性和安全性及其对尿失禁结果的影响。方法113例接受LRP的患者被随机分为两组：第1组（n？=？57）在POD 2上取下导尿管，而第2组（n？=？56）在POD 4上取下导尿管。尿流失率（ULR）定义为尿垫中尿流失的重量除以每日排尿量。失禁被定义为无垫状态。结果第1组和第2组之间的临床特征无显着差异。第1组和第8组中有21例患者发生急性尿retention留（AUR）（18.6％）（13％（22.8％）），第8组（14.3 %%）第2组的第一天平均ULR值为1.16±±4.95，第2组的第一天平均ULR值为1.02±±3.27（p≥0.870）。第1组为0.57？±？1.60，第2组为2.78？±？15.49（p？=？0.353），第3、6、9和12个月的节制率为21.8、41.1、58.0和71.4？第1组中的％和第2组中的34.5％，66.0％，79.2％和83.7％（分别为p？=？0.138、0.009、0.024和0.146）。在AUR病例中，节制率为3、6、9和12。第1组的0个月为0、23.1、38.5和54.5％，第2组的3个月为37.5、75.0、87.5和87.5％（分别为p？= 0.017、0.020、0.027和0.127）。在POD 2上取下导管后，AUR被确定为LRP后6和9个月尿失禁的唯一预测因素（分别为p？= 0.030和0.018）。包涵体我们的结果表明，LRP后过早在POD 2上拔除导管可能会增加失禁的风险。试验注册该研究已注册为临床试验：（UMIN000014944）;注册日期：2012年3月12日。

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