...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>BMC research notes >A novel long term short interval physical activity regime improves body composition in mice
【24h】

A novel long term short interval physical activity regime improves body composition in mice

机译：一种新颖的长期短间隔体育锻炼机制可改善小鼠的身体成分

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background Exercise training (ET) and physical activity (PA) offer obvious health benefits in regular participants. In pre-clinical animal models, treadmills and running wheels are the models of choice for intervention studies using ET and PA. However, the frequency and duration necessary for positive effects on health are not completely understood. We investigated the impact of short duration voluntary wheel running on body composition in FVB × C57BL /6?F1 hybrid mice over 22?weeks. Mice were randomized and given access to voluntary wheel running (N?=?6) or locked wheels (N?=?5) for 1?hour per night during the dark cycle, 5?days per week. Finding Average weekly running distance was generally cyclic in nature over the 22?weeks but did not change significantly from week to week, except for a difference between week 3 and week 9 (P?=?0.05). Daily running distances ranged from 0.78?km to 1.45?km. Compared with non-runners, runners demonstrated significantly lower relative fat mass (9.98?±?0.56% vs. 14.91?±?1.47%, P?=?0.0067) and significantly higher relative lean mass (79.18?±?0.65% vs. 75.41?±?1.28%, P?=?0.019). No differences were observed with respect to glucose metabolism. Conclusion Voluntary wheel running for one hour a day five days a week over a five month period improved body composition in young adult mice. This repetitive short interval exercise regime should be a useful model to investigate the effects of structured moderate intensity physical activity on physiological performance and chronic disease conditions in mice.
机译：背景运动训练（ET）和体育锻炼（PA）为普通参与者带来明显的健康益处。在临床前动物模型中，跑步机和跑轮是使用ET和PA进行干预研究的首选模型。但是，对健康产生积极影响所需的频率和持续时间尚未完全了解。我们调查了短时自愿轮行驶对FVB×C57BL / 6？F1杂种小鼠22周内身体成分的影响。小鼠被随机分配，并在黑暗周期中每晚1小时每小时（每周5天）使用自愿轮（N≥6）或锁定车轮（N≥5）。结果发现，在22周内，平均每周跑步距离通常具有周期性，但除了第3周和第9周之间的差异外，各周之间没有显着变化（P≥0.05）。每日行驶距离从0.78公里到1.45公里。与非跑步者相比，跑步者的相对脂肪质量显着降低（9.98％±0.56％比14.91％±1.47％，P％= 0.0067），相对瘦体重显着较高（79.18％±0.65％vs. 75.41±±1.28％，P≥0.019）。在葡萄糖代谢方面未观察到差异。结论在五个月的时间内，每周五天每天进行一小时的自愿轮转可以改善成年小鼠的身体组成。这种重复性的短间隔运动方式应该是一个有用的模型，以研究结构化的中等强度的体育活动对小鼠的生理表现和慢性疾病状况的影响。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号