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Prevalence and risk factors of chronic obstructive pulmonary disease in Anhui Province, China: a population-based survey

机译:中国安徽省慢性阻塞性肺疾病的患病率和危险因素:基于人群的调查

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The prevalence of chronic obstructive pulmonary disease (COPD) in Anhui Province of eastern China remain uncertain. The present study provides the first estimate of the prevalence and risk factors of COPD in Anhui. A population-based survey was conducted in a representative sample of population aged 40?years or older in 2015. COPD was diagnosed based on 2017 Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria. A total of 2770 participants had reliable post-bronchodilator results and were included in the final analysis. The overall prevalence of COPD was 9.8% (95% CI: 8.2, 11.7). Prevalence was higher in men (14.8, 95% CI: 12.6, 17.2) than it was in women (5.2, 95% CI: 3.1, 8.7). Among adults with COPD, 45.0% (95% CI: 39.1, 51.0) had moderate or severe disease (GOLD stage II-IV), 0.7% (95% CI: 0.2, 2.9) reported that they had a previous pulmonary function test, and only 0.4% (95% CI: 0.1, 2.6) knew their diagnosis of COPD. Risk factors for COPD included older age (OR 1.06, 95% CI: 1.04, 1.08), male sex (OR 2.01, 95% CI: 1.22, 3.33), current smoking status (OR 2.63, 95% CI: 1.86, 3.73), primary school or lower education (OR 1.61, 95% CI: 1.12, 2.31), family history of lung disease (OR 1.50, 95% CI: 1.17, 1.93), and indoor exposure to coal for cooking or heating (OR 1.55, 95% CI: 1.11, 2.15). In addition, people in north region has a significantly higher risk for developing COPD than people in south region of Anhui (OR 1.98, 95% CI:1.44, 2.71). COPD is prevalent in Anhui and the prevalence is highest in north region. Strategies aiming at prevention, early detection and treatment of COPD are urgently needed to reduce COPD-related burden.
机译:中国东部安徽省的慢性阻塞性肺疾病(COPD)患病率仍不确定。本研究提供了对安徽省COPD患病率和危险因素的初步估计。在2015年,对40岁或40岁以上人口的代表性样本进行了基于人口的调查。根据2017年全球慢性阻塞性肺病倡议(GOLD)标准,诊断出COPD。共有2770名参与者具有可靠的支气管扩张剂使用后结果,并被纳入最终分析。 COPD的整体患病率为9.8%(95%CI:8.2,11.7)。男性(14.8,95%CI:12.6,17.2)患病率高于女性(5.2,95%CI:3.1,8.7)。在患有COPD的成年人中,有45.0%(95%CI:39.1,51.0)患有中度或重度疾病(GOLD II-IV期),0.7%(95%CI:0.2,2.9)曾接受过肺功能检查,只有0.4%(95%CI:0.1,2.6)知道他们对COPD的诊断。 COPD的危险因素包括年龄较大(OR 1.06,95%CI:1.04,1.08),男性(OR 2.01,95%CI:1.22,3.33),当前吸烟状况(OR 2.63,95%CI:1.86,3.73) ,小学或较低学历(OR 1.61,95%CI:1.12,2.31),肺部疾病的家族病史(OR 1.50,95%CI:1.17,1.93),以及室内暴露于做饭或取暖的煤中(OR 1.55, 95%CI:1.11、2.15)。此外,北部地区人群患COPD的风险明显高于安徽南部地区(OR 1.98,95%CI:1.44,2.71)。 COPD在安徽流行,在北部地区患病率最高。迫切需要采取旨在预防,及早发现和治疗COPD的策略,以减轻与COPD相关的负担。

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