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首页> 外文期刊>BMC Surgery >Efficacy and safety profile of a novel technique, ThuLEP (Thulium laser enucleation of the prostate) for the treatment of benign prostate hypertrophy. Our experience on 148 patients
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Efficacy and safety profile of a novel technique, ThuLEP (Thulium laser enucleation of the prostate) for the treatment of benign prostate hypertrophy. Our experience on 148 patients

机译：一种新技术ThuLEP（前列腺的hu激光去核）的功效和安全性概况。我们对148位患者的经验

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BackgroundOver the past years laser technology has played a predominant role in prostate surgery, for the treatment of benign prostate hypertrophy (BPH). Various laser devices have been introduced in clinical practice, showing good results in terms of complications and urodynamic outcomes efficacy compared with TURP and Open Prostatectomy.In this study we describe the efficacy and the safety profile of a novel laser technique, ThuLEP (Thulium Laser Enucleation of Prostate) that permits a complete anatomical endoscopic enucleation of prostatic adenoma independently to prostate size.Methods148 patients with a mean age of 68.2 years were enrolled between September 2009 and March 2012 (36 months), and treated for BPH with ThuLEP. Every patient was evaluated at base line according to: Digital Rectal Examination (DRE), prostate volume, Post-Voided volume (PVR), International Prostate Symptoms Score (I-PSS), International Index of Erectile Function-5 (IIEF-5), Quality of Life (QoL), PSA values, urine analysis and urine culture, uroflowmetry. The same evaluation was conducted after a 12 month follow-up. ThuLEP was performed by 2 expert surgeons.ResultsOur data showed a better post-operative outcome in terms of catheter removal, blood loss, TURP syndrome, clot retention and residual tissue compared to large series of TURP and OP. Only 1.3% of patients had bladder wall injury during morcellation. I-PSS, Qmax, Prostate Volume, QoL and PVR showed a highly significant improvement at 12 month follow-up in comparison to preoperative assessment.ConclusionThuLEP represent an innovative option in patients with BPH. It is a size independent surgical endoscopic technique and it can be considered the real alternative, at this time, to TURP and even more to Open Prostatectomy for large prostate, with a complete removal of adenoma and with a low complication rate.
机译：背景技术在过去的几年中，激光技术在前列腺手术中起着重要的作用，用于治疗良性前列腺肥大（BPH）。在临床实践中已经引入了各种激光设备，与TURP和开放式前列腺切除术相比，在并发症和尿动力学结果疗效方面均显示出了良好的效果。方法148例平均年龄为68.2岁的患者在2009年9月至2012年3月（36个月）之间入选，并接受ThuLEP治疗以治疗BPH。根据以下各项对每位患者进行基线评估：数字直肠检查（DRE），前列腺体积，排尿后体积（PVR），国际前列腺症状评分（I-PSS），国际勃起功能指数5（IIEF-5） ，生活质量（QoL），PSA值，尿液分析和尿液培养，尿流仪。在12个月的随访后进行了相同的评估。 ThuLEP由2位专业的外科医生进行。结果我们的数据显示，与大量的TURP和OP相比，在导管去除，失血，TURP综合征，凝块保留和残留组织方面，术后结局更好。在拆解期间只有1.3％的患者患有膀胱壁损伤。与术前评估相比，I-PSS，Qmax，前列腺体积，QoL和PVR在术后12个月的随访中显示出非常显着的改善。结论ThuLEP是BPH患者的一种创新选择。这是一种不依赖于大小的外科手术内窥镜技术，目前可以认为它是TURP的真正替代方案，对于大型前列腺癌，甚至可以完全切除腺瘤且并发症发生率低，甚至可以替代开放式前列腺切除术。

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