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首页> 外文期刊>Brazilian Journal of Infectious Diseases >Incidence and clinical characteristics of the infection by the Respiratory Syncytial Virus in children admitted in Santa Casa de S?o Paulo Hospital
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Incidence and clinical characteristics of the infection by the Respiratory Syncytial Virus in children admitted in Santa Casa de S?o Paulo Hospital

机译:圣保罗圣保罗医院收治的儿童呼吸道合胞病毒感染的发生率和临床特征

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The purpose of this study was to identify the rate of infections due to RSV and other viruses in children. In addition we have analyzed demographic data and clinical characteristics of the RSV-positive patients comparing with patients infected by other respiratory viruses. We also described the seasonality of the RSV occurrence in a hospital in S?o Paulo. Children below 5 years old admitted in Santa Casa de S?o Paulo Hospital between February 2005 and September 2006 due to acute respiratory infections (ARI) were included. A nasopharyngeal specimens were obtained with sterile No. 5 French feeding catheters as soon as possible (usually within 24 h). Specimens were kept refrigerated at 4oC and transported to Adolfo Lutz Institute, where the indirect immunofluorescent assay was performed. Virus identified by these assay included RSV, Adenovirus, Influenza A and B virus and Parainfluenza 1, 2, and 3. Clinical data from each group was compared. Four hundred and fifty five cases were included in the study, with 30% positive for some type of virus. Viruses that were identified included Respiratory Syncytial Virus (73.03%), Influenza (8.42%), Parainfluenza (8.42%) and Adenovirus (3.37%). We divided the subjects in 3 groups: Group 1 RSV-Positive, Group 2 Other Positive Viruses and Group 3 Negative for Respiratory Virus. Mean age (months) was of 7.5 for RSV-positive children, 7.6 for other viruses, and 8 for negative for respiratory virus. The RSV-Positive Group was significantly younger than the Group Negative for Respiratory Virus (p
机译:这项研究的目的是确定儿童RSV和其他病毒引起的感染率。此外,我们还分析了RSV阳性患者与其他呼吸道病毒感染患者的人口统计学数据和临床特征。我们还描述了圣保罗一家医院中RSV发生的季节性。其中包括2005年2月至2006年9月之间因急性呼吸道感染(ARI)在圣保罗圣保罗医院住院的5岁以下儿童。尽快(通常在24小时内)用无菌5号法国饲喂导管获得鼻咽标本。将标本保存在4oC的冰箱中,然后运送到Adolfo Lutz研究所,在那里进行间接免疫荧光测定。通过这些测定鉴定的病毒包括RSV,腺病毒,甲型和乙型流感病毒以及副流感1、2和3。比较了每组的临床数据。该研究包括455例病例,其中某种病毒阳性率为30%。确定的病毒包括呼吸道合胞病毒(73.03%),流感(8.42%),副流感(8.42%)和腺病毒(3.37%)。我们将受试者分为3组:第1组RSV阳性,第2组其他阳性病毒和第3组呼吸道病毒阴性。 RSV阳性儿童的平均年龄(月)为7.5,其他病毒为7.6,呼吸道病毒阴性为8。 RSV阳性组比呼吸道病毒阴性组显着年轻(p

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